Neurology updates

The 2017 McDonald criteria showed higher sensitivity, lower specificity, and similar accuracy in predicting clinically definite multiple sclerosis compared to 2010 McDonald criteria, while shortening time to its diagnosis.

Insidious disability accrual starts already in the earliest phases of multiple sclerosis and becomes dominant over the disease course, suggesting an ongoing process of inflammation and/or degeneration secondary to disease burden.

Epstein-Barr virus infection is the strongest known risk factor for the development of multiple sclerosis, and it precedes preclinical manifestation of the disease suggesting a possible causal role

In multiple sclerosis, an impairment of the glymphatic system may contribute to pathology accrual in the central nervous system and disability progression.

Baseline characteristics of Aβ-positive individuals can help identify those who will remain tau-negative for at least 5 years.

Greater diffusion restriction in the white matter of amyloid-beta-positive cognitively unimpaired individuals supports the role of inflammation in early preclinical AD.

New Neurology Update from Stroke Scientific Panel

The revised Boston criteria allow for a more accurate diagnosis of cerebral amyloid angiopathy

WGS can reliably assess the most common neurological disease-causing repeat expansions, further supporting its implementation in clinical practice.

New Neurology Update from Palliative Care is in! Read more about the topics here

Palliative care outpatient clinics, with a multidisciplinary team, helps patients with Parkinson’s disease and related disorders and their families.

Event Related Potentials might be an accurate neurophysiological biomarker for early diagnosis of AD and prediction of MCI to AD conversion.

Two patients with severe PML have been successfully treated with BK virus-specific T cells at Hannover Medical School's Department of Neurology, according to director, Prof. Günter Höglinger.

Archeological neuroimmunology- pathogenic immune response from a case of more than 60 years ago characterized from archival brain tissue

Neurology Update: Epilepsy