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  • EAN News
    • All Executive Page EAN News EAN Congress news Interviews
      EAN News

      Plans in progress for 30th Anniversary of the European Journal of Neurology (1994-2024)

      December 6, 2023

      Advocacy

      Executive Page: European neurology united as ever heading into milestone year

      December 6, 2023

      Paper of the Month

      Research Paper of the Month: Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation

      December 4, 2023

      Research Highlights One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – December 2023

      December 1, 2023

      Executive Page

      Executive Page: European neurology united as ever heading into milestone year

      December 6, 2023

      Executive Page

      Executive Page: Join or renew your membership now and celebrate 10 years of the EAN

      November 6, 2023

      Executive Page

      Executive Page: Advocacy for brain health gaining momentum across the neurological landscape

      October 1, 2023

      Executive Page Dear EAN members, dear friends, It is my pleasure to give you an update on behalf of the EAN Scientific Committee following a busy year since my appointment as chair. It has been a privilege to be so deeply involved in the scientific activities of the EAN and to work closely with an amazing community of people who are so dedicated to the advancement of neurology. One of the strongest threads within that community is the EAN’s group of Scientific Panels, which are often referred to as the organisation’s ‘scientific backbone’. The panels have a hand in everything the EAN does from a scientific point of view, including coordinating clinical research, disseminating good practice, assisting in planning the EAN annual congress, supporting the EAN’s educational efforts, and producing guidelines that assist neurologists in daily practice. All of this work requires a considerable amount of oversight, and this is why each panel is run by its own Management Group, elected by the panel members. Being a part of one of these Management Groups (PDF) is an opportunity to play a direct part in determining the direction of scientific progress within Europe, and I am excited to say that the call for applications to stand for election will be announced in September. All panel members and EAN individual members are eligible to apply to be candidates, with the vote being held among the existing panel members in autumn. I would like to urge every neurologist with a passion for the scientific future of their special area of interest to consider standing for election to the relevant Management Group and to look out for the call for applications later this month. I can tell you from personal experience that fulfilling a role such as this within the structure of the EAN is a fascinating and extremely rewarding experience. The chance to take on such a unique leadership position should not be missed! The most satisfying aspect of being involved in the EAN’s organisational structure is surely seeing all the hard work and planning come to fruition when a small idea evolves into a newly launched project. One such example is the 1st EAN Science School, taking place in Salzburg next March. The idea of the Science School is to offer early career neurologists with an interest in translational research a new avenue for learning about basic pathomechanisms of neurological disorders. Application for this very first edition, on ‘Pathophysiology of disorders of the nervous system’, closed last week and we have been delighted with the level of interest. It was a pleasure to be part of the task force in charge of planning this new project and I look forward to seeing it officially transferred to the hands of the Scientific Committee after a successful event and evaluation in spring. Of our ongoing activities, one of the most significant is the EAN Neuro-covid Registry, which aims to collate epidemiological data on neurological manifestations in patients with COVID-19 infection reported by neurologists in outpatient services, emergency rooms, and hospital departments. We currently have 1,542 patients entered in the database, from 35 centres across 23 countries. So far, 29 patients have been followed for 12 months and 387 have completed the 6-months follow up. This is a decent start, but I would like to strongly encourage EAN members and their institutions to get involved and contribute cases to what will become an invaluable resource for neurologists and clinicians to improve care for Covid-19 patients. Finally, I would like share a word on a forthcoming collaboration between EAN and the Human Brain Project in December, that I think will interest a lot of EAN members. The EAN-EBRAINS joint workshop on ‘The future of medical data sharing in clinical neurosciences’ will be a three-day virtual event that aims to discuss issues and challenges associated with data sharing in Europe, from ethics to data safety and privacy, including those specific to data federation, such as the development and validation of federated algorithms. The whole workshop is completely free of charge and registration is open until 25 November, so please check out the details and sign up! I wish you all a healthy and pleasant autumn and I look forward to updating you again. Best wishes Thomas Berger Chair of the EAN Scientific Committee

      Executive Page: Management Group elections are coming – run for office and help shape our future!

      September 1, 2023

      EAN News

      Plans in progress for 30th Anniversary of the European Journal of Neurology (1994-2024)

      December 6, 2023

      EAN News

      Executive Page: European neurology united as ever heading into milestone year

      December 6, 2023

      EAN News

      Research Paper of the Month: Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation

      December 4, 2023

      EAN News One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – December 2023

      December 1, 2023

      EAN Congress news

      EAN 2024 – Abstract submission and registration OPEN!

      November 22, 2023

      EAN Congress news

      Burden of Sleep/Wake Disorders Project at EAN Congress 2023

      October 19, 2023

      EAN Congress news

      African Academy of Neurology features in Special Studio Session at EAN 2023

      July 25, 2023

      EAN Congress news

      Find photos, facts, figures and reports in our EAN Congress Review

      July 24, 2023

      Interviews

      Video Interview: Prof. Mary Reilly, Moritz Romberg lecturer at EAN 2023

      July 4, 2023

      Interviews

      Video Interview: Mark Hallett, C. Brown-Séquard lecturer at EAN 2023

      July 3, 2023

      Interviews

      Video Interview: Josep Dalmau, Camillo Golgi Lecturer at EAN 2023

      July 2, 2023

      Interviews

      Video Interview: Dementia & Cognitive Disorders Panel Co-Chairs

      September 8, 2022

  • Research
    • All Paper of the Month Research Highlights
      Paper of the Month

      Research Paper of the Month: Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation

      December 4, 2023

      Research Highlights One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – December 2023

      December 1, 2023

      Paper of the Month

      Research Paper of the Month: Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH)

      November 6, 2023

      Research Highlights One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – November 2023

      November 6, 2023

      Paper of the Month

      Research Paper of the Month: Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation

      December 4, 2023

      Paper of the Month

      Research Paper of the Month: Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH)

      November 6, 2023

      Paper of the Month

      Research Paper of the Month: Transdermal Nicotine Treatment and Progression of Early Parkinson’s Disease

      October 1, 2023

      Paper of the Month

      Research Paper of the Month: Soluble Nogo-Receptor-Fc decoy (AXER-204) in patients with chronic cervical spinal cord injury in the USA

      September 1, 2023

      Research Highlights One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – December 2023

      December 1, 2023

      Research Highlights One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – November 2023

      November 6, 2023

      Research Highlights One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – October 2023

      October 1, 2023

      Research Highlights One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – September 2023

      September 1, 2023

  • Education
    • All eLearning Student Corner Resident and Research Fellows Fellowship reports
      eLearning

      End 2023 with highlighted content on the eanCampus!

      December 2, 2023

      Resident and Research Fellows

      EAN Spring School 2024 – Apply NOW until 31 January 2024

      December 1, 2023

      Resident and Research Fellows

      EAN Autumn School 2023: Report

      November 30, 2023

      eLearning

      Call for Applications: e-Learning Platform Associate Editors

      November 7, 2023

      eLearning

      End 2023 with highlighted content on the eanCampus!

      December 2, 2023

      eLearning

      Call for Applications: e-Learning Platform Associate Editors

      November 7, 2023

      eLearning

      Kick off the new season with highlights on the eanCampus

      October 13, 2023

      eLearning

      World Brain Day with the European Academy of Neurology

      July 21, 2023

      Student Corner

      Student Teaser Fellowship reports 2022 – Pisa, London, & Lausanne

      September 13, 2023

      Student Corner Illustration of a vertical pencil point on a blue background, with a yellow light bulb above it

      Student Corner: My EAN Congress experience

      September 5, 2023

      Student Corner

      Student Teaser Fellowship reports 2022 – Rotterdam, London, & Paris

      August 22, 2023

      Student Corner

      Student Teaser Fellowship winners 2023

      June 28, 2023

      Resident and Research Fellows

      EAN Spring School 2024 – Apply NOW until 31 January 2024

      December 1, 2023

      Resident and Research Fellows

      EAN Autumn School 2023: Report

      November 30, 2023

      Resident and Research Fellows

      Research Fellowship Report 2022 – Oxford Autoimmune Neurology Group

      September 16, 2023

      Resident and Research Fellows

      Research Fellowship Report 2022 – Centre Hospitalier Universitaire Vaudois, Lausanne

      September 15, 2023

      Fellowship reports

      Research Fellowship Report 2022 – Oxford Autoimmune Neurology Group

      September 16, 2023

      Fellowship reports

      Research Fellowship Report 2022 – Centre Hospitalier Universitaire Vaudois, Lausanne

      September 15, 2023

      Fellowship reports

      Research Fellowship Report 2022 – Department of Neuromuscular Diseases Institute, University College London

      September 14, 2023

      Fellowship reports

      Student Teaser Fellowship reports 2022 – Pisa, London, & Lausanne

      September 13, 2023

  • Other News
    • All EAN Staff EBC News in general Surveys
      EAN Staff

      EAN Head Office Profiles: Ulla & Piyapat

      December 1, 2023

      EAN Staff

      EAN Head Office Profiles: Maria & Immanuel

      November 7, 2023

      Advocacy

      Brain community launches Call to Action during Brain Health & Research Day at UNGA78

      October 19, 2023

      EAN News

      Brain Innovation Days 2023: Meet the speakers!

      October 2, 2023

      EAN Staff

      EAN Head Office Profiles: Ulla & Piyapat

      December 1, 2023

      EAN Staff

      EAN Head Office Profiles: Maria & Immanuel

      November 7, 2023

      EAN Staff

      EAN Head Office Profiles: Kathrin & Sasha

      August 28, 2023

      EAN Staff Anja Sander receiving flowers at the end of EAN Congress 2023

      Celebrating 20 Years of Excellence: Anja Sander, EAN’s Executive Director!

      August 3, 2023

      EBC

      Brain community launches Call to Action during Brain Health & Research Day at UNGA78

      October 19, 2023

      EBC

      Brain Innovation Days 2023: Meet the speakers!

      October 2, 2023

      EBC

      Brain Innovation Days: Discover the early programme and register today!

      July 21, 2023

      EBC

      Join the community’s calls for a European Brain Research and Innovation Plan

      July 21, 2023

      News in general

      WHO’s Intersectoral Global Action Plan on epilepsy and other neurological disorders (IGAP) published in all six UN languages

      August 3, 2023

      News in general

      WHO recognises the public health need for effective and affordable treatments for multiple sclerosis

      August 3, 2023

      News in general

      Brain Innovation Days: Discover the early programme and register today!

      July 21, 2023

      News in general

      Join the community’s calls for a European Brain Research and Innovation Plan

      July 21, 2023

      Surveys

      Neurorehabilitation Across Europe after Ischemic and Traumatic Brain Injuries: a survey to increase knowledge on brain-injury-specific neurorehabilitation

      July 14, 2023

      Surveys

      ILAE survey on genetic testing in the epilepsies

      July 14, 2023

      Surveys

      COVID-19 and neurology: a survey of previous and continued restrictions on clinical practice, professional education and neuroeconomics

      March 3, 2023

      Surveys

      Help EAN contribute towards the development of a European Pain Research strategy

      December 5, 2022

  • EAN
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eanpages

  • EAN News
    • All Executive Page EAN News EAN Congress news Interviews
      EAN News

      Plans in progress for 30th Anniversary of the European Journal of Neurology (1994-2024)

      December 6, 2023

      Advocacy

      Executive Page: European neurology united as ever heading into milestone year

      December 6, 2023

      Paper of the Month

      Research Paper of the Month: Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation

      December 4, 2023

      Research Highlights One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – December 2023

      December 1, 2023

      Executive Page

      Executive Page: European neurology united as ever heading into milestone year

      December 6, 2023

      Executive Page

      Executive Page: Join or renew your membership now and celebrate 10 years of the EAN

      November 6, 2023

      Executive Page

      Executive Page: Advocacy for brain health gaining momentum across the neurological landscape

      October 1, 2023

      Executive Page Dear EAN members, dear friends, It is my pleasure to give you an update on behalf of the EAN Scientific Committee following a busy year since my appointment as chair. It has been a privilege to be so deeply involved in the scientific activities of the EAN and to work closely with an amazing community of people who are so dedicated to the advancement of neurology. One of the strongest threads within that community is the EAN’s group of Scientific Panels, which are often referred to as the organisation’s ‘scientific backbone’. The panels have a hand in everything the EAN does from a scientific point of view, including coordinating clinical research, disseminating good practice, assisting in planning the EAN annual congress, supporting the EAN’s educational efforts, and producing guidelines that assist neurologists in daily practice. All of this work requires a considerable amount of oversight, and this is why each panel is run by its own Management Group, elected by the panel members. Being a part of one of these Management Groups (PDF) is an opportunity to play a direct part in determining the direction of scientific progress within Europe, and I am excited to say that the call for applications to stand for election will be announced in September. All panel members and EAN individual members are eligible to apply to be candidates, with the vote being held among the existing panel members in autumn. I would like to urge every neurologist with a passion for the scientific future of their special area of interest to consider standing for election to the relevant Management Group and to look out for the call for applications later this month. I can tell you from personal experience that fulfilling a role such as this within the structure of the EAN is a fascinating and extremely rewarding experience. The chance to take on such a unique leadership position should not be missed! The most satisfying aspect of being involved in the EAN’s organisational structure is surely seeing all the hard work and planning come to fruition when a small idea evolves into a newly launched project. One such example is the 1st EAN Science School, taking place in Salzburg next March. The idea of the Science School is to offer early career neurologists with an interest in translational research a new avenue for learning about basic pathomechanisms of neurological disorders. Application for this very first edition, on ‘Pathophysiology of disorders of the nervous system’, closed last week and we have been delighted with the level of interest. It was a pleasure to be part of the task force in charge of planning this new project and I look forward to seeing it officially transferred to the hands of the Scientific Committee after a successful event and evaluation in spring. Of our ongoing activities, one of the most significant is the EAN Neuro-covid Registry, which aims to collate epidemiological data on neurological manifestations in patients with COVID-19 infection reported by neurologists in outpatient services, emergency rooms, and hospital departments. We currently have 1,542 patients entered in the database, from 35 centres across 23 countries. So far, 29 patients have been followed for 12 months and 387 have completed the 6-months follow up. This is a decent start, but I would like to strongly encourage EAN members and their institutions to get involved and contribute cases to what will become an invaluable resource for neurologists and clinicians to improve care for Covid-19 patients. Finally, I would like share a word on a forthcoming collaboration between EAN and the Human Brain Project in December, that I think will interest a lot of EAN members. The EAN-EBRAINS joint workshop on ‘The future of medical data sharing in clinical neurosciences’ will be a three-day virtual event that aims to discuss issues and challenges associated with data sharing in Europe, from ethics to data safety and privacy, including those specific to data federation, such as the development and validation of federated algorithms. The whole workshop is completely free of charge and registration is open until 25 November, so please check out the details and sign up! I wish you all a healthy and pleasant autumn and I look forward to updating you again. Best wishes Thomas Berger Chair of the EAN Scientific Committee

      Executive Page: Management Group elections are coming – run for office and help shape our future!

      September 1, 2023

      EAN News

      Plans in progress for 30th Anniversary of the European Journal of Neurology (1994-2024)

      December 6, 2023

      EAN News

      Executive Page: European neurology united as ever heading into milestone year

      December 6, 2023

      EAN News

      Research Paper of the Month: Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation

      December 4, 2023

      EAN News One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – December 2023

      December 1, 2023

      EAN Congress news

      EAN 2024 – Abstract submission and registration OPEN!

      November 22, 2023

      EAN Congress news

      Burden of Sleep/Wake Disorders Project at EAN Congress 2023

      October 19, 2023

      EAN Congress news

      African Academy of Neurology features in Special Studio Session at EAN 2023

      July 25, 2023

      EAN Congress news

      Find photos, facts, figures and reports in our EAN Congress Review

      July 24, 2023

      Interviews

      Video Interview: Prof. Mary Reilly, Moritz Romberg lecturer at EAN 2023

      July 4, 2023

      Interviews

      Video Interview: Mark Hallett, C. Brown-Séquard lecturer at EAN 2023

      July 3, 2023

      Interviews

      Video Interview: Josep Dalmau, Camillo Golgi Lecturer at EAN 2023

      July 2, 2023

      Interviews

      Video Interview: Dementia & Cognitive Disorders Panel Co-Chairs

      September 8, 2022

  • Research
    • All Paper of the Month Research Highlights
      Paper of the Month

      Research Paper of the Month: Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation

      December 4, 2023

      Research Highlights One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – December 2023

      December 1, 2023

      Paper of the Month

      Research Paper of the Month: Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH)

      November 6, 2023

      Research Highlights One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – November 2023

      November 6, 2023

      Paper of the Month

      Research Paper of the Month: Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation

      December 4, 2023

      Paper of the Month

      Research Paper of the Month: Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH)

      November 6, 2023

      Paper of the Month

      Research Paper of the Month: Transdermal Nicotine Treatment and Progression of Early Parkinson’s Disease

      October 1, 2023

      Paper of the Month

      Research Paper of the Month: Soluble Nogo-Receptor-Fc decoy (AXER-204) in patients with chronic cervical spinal cord injury in the USA

      September 1, 2023

      Research Highlights One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – December 2023

      December 1, 2023

      Research Highlights One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – November 2023

      November 6, 2023

      Research Highlights One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – October 2023

      October 1, 2023

      Research Highlights One glowing light bulb that stands out from unlit or dim lamps on a blue background

      Research Highlights of the Month – September 2023

      September 1, 2023

  • Education
    • All eLearning Student Corner Resident and Research Fellows Fellowship reports
      eLearning

      End 2023 with highlighted content on the eanCampus!

      December 2, 2023

      Resident and Research Fellows

      EAN Spring School 2024 – Apply NOW until 31 January 2024

      December 1, 2023

      Resident and Research Fellows

      EAN Autumn School 2023: Report

      November 30, 2023

      eLearning

      Call for Applications: e-Learning Platform Associate Editors

      November 7, 2023

      eLearning

      End 2023 with highlighted content on the eanCampus!

      December 2, 2023

      eLearning

      Call for Applications: e-Learning Platform Associate Editors

      November 7, 2023

      eLearning

      Kick off the new season with highlights on the eanCampus

      October 13, 2023

      eLearning

      World Brain Day with the European Academy of Neurology

      July 21, 2023

      Student Corner

      Student Teaser Fellowship reports 2022 – Pisa, London, & Lausanne

      September 13, 2023

      Student Corner Illustration of a vertical pencil point on a blue background, with a yellow light bulb above it

      Student Corner: My EAN Congress experience

      September 5, 2023

      Student Corner

      Student Teaser Fellowship reports 2022 – Rotterdam, London, & Paris

      August 22, 2023

      Student Corner

      Student Teaser Fellowship winners 2023

      June 28, 2023

      Resident and Research Fellows

      EAN Spring School 2024 – Apply NOW until 31 January 2024

      December 1, 2023

      Resident and Research Fellows

      EAN Autumn School 2023: Report

      November 30, 2023

      Resident and Research Fellows

      Research Fellowship Report 2022 – Oxford Autoimmune Neurology Group

      September 16, 2023

      Resident and Research Fellows

      Research Fellowship Report 2022 – Centre Hospitalier Universitaire Vaudois, Lausanne

      September 15, 2023

      Fellowship reports

      Research Fellowship Report 2022 – Oxford Autoimmune Neurology Group

      September 16, 2023

      Fellowship reports

      Research Fellowship Report 2022 – Centre Hospitalier Universitaire Vaudois, Lausanne

      September 15, 2023

      Fellowship reports

      Research Fellowship Report 2022 – Department of Neuromuscular Diseases Institute, University College London

      September 14, 2023

      Fellowship reports

      Student Teaser Fellowship reports 2022 – Pisa, London, & Lausanne

      September 13, 2023

  • Other News
    • All EAN Staff EBC News in general Surveys
      EAN Staff

      EAN Head Office Profiles: Ulla & Piyapat

      December 1, 2023

      EAN Staff

      EAN Head Office Profiles: Maria & Immanuel

      November 7, 2023

      Advocacy

      Brain community launches Call to Action during Brain Health & Research Day at UNGA78

      October 19, 2023

      EAN News

      Brain Innovation Days 2023: Meet the speakers!

      October 2, 2023

      EAN Staff

      EAN Head Office Profiles: Ulla & Piyapat

      December 1, 2023

      EAN Staff

      EAN Head Office Profiles: Maria & Immanuel

      November 7, 2023

      EAN Staff

      EAN Head Office Profiles: Kathrin & Sasha

      August 28, 2023

      EAN Staff Anja Sander receiving flowers at the end of EAN Congress 2023

      Celebrating 20 Years of Excellence: Anja Sander, EAN’s Executive Director!

      August 3, 2023

      EBC

      Brain community launches Call to Action during Brain Health & Research Day at UNGA78

      October 19, 2023

      EBC

      Brain Innovation Days 2023: Meet the speakers!

      October 2, 2023

      EBC

      Brain Innovation Days: Discover the early programme and register today!

      July 21, 2023

      EBC

      Join the community’s calls for a European Brain Research and Innovation Plan

      July 21, 2023

      News in general

      WHO’s Intersectoral Global Action Plan on epilepsy and other neurological disorders (IGAP) published in all six UN languages

      August 3, 2023

      News in general

      WHO recognises the public health need for effective and affordable treatments for multiple sclerosis

      August 3, 2023

      News in general

      Brain Innovation Days: Discover the early programme and register today!

      July 21, 2023

      News in general

      Join the community’s calls for a European Brain Research and Innovation Plan

      July 21, 2023

      Surveys

      Neurorehabilitation Across Europe after Ischemic and Traumatic Brain Injuries: a survey to increase knowledge on brain-injury-specific neurorehabilitation

      July 14, 2023

      Surveys

      ILAE survey on genetic testing in the epilepsies

      July 14, 2023

      Surveys

      COVID-19 and neurology: a survey of previous and continued restrictions on clinical practice, professional education and neuroeconomics

      March 3, 2023

      Surveys

      Help EAN contribute towards the development of a European Pain Research strategy

      December 5, 2022

Interviews

Interview with Olivier Rascol

December 1, 2014

Rascol_OlivierOlivier Rascol is Professor of Clinical Pharmacology at the University Hospital in Toulouse, France and Chair of the Movement Disorder Society-European Section
(MDS-ES)

Gian Luigi Lenzi (GLL): As Chair of the MDS-European Section, can you illustrate the role you would like the EAN to cover within the world of European Neurology?

Olivier Rascol (OR): In my view, the EAN has crucial strategic and practical roles to cover in order to reinforce the knowledge of neurological disorders and improve the care of neurological patients in Europe and worldwide. As the strongest and unique Society promoting Clinical Neurology in Europe, the EAN will collaborate with patient associations, other scientific societies, regulatory agencies, pharmaceutical industries and other comparable international entities like for example the American Academy of Neurology. This will allow defining strategic roadmaps to develop and improve key issues related to neurology, including communication and awareness, education, best medical practice and management, research, etc… The EAN will obviously work towards excellence in education and training in neurology, producing recommendations and guidelines in this field and pay efforts in reducing the gap in the care of neurological disorders throughout Europe. I also expect that the EAN will be a forum encouraging cross-interest approaches and bridging gaps between the different sub-specialties of neurology, between pre-clinical and clinical research and opening more broadly neurological sciences to the society and its needs.

GLL: It is the EAN’s goal is to be the overall umbrella for neurology and neurology related specialties. How do you see MDS – European Section working together with the EAN? Which kind of educational as well as cultural initiatives can be initiated together by the EAN and the MDS-European Section?

OR: Most movement disorders are caused by neurological disorders. As so, improving their knowledge and the care of patients suffering from such disorders in Europe is in the scope of 2 major societies, namely the EAN and the International Parkinson disease and Movement Disorders Society (MDS). The MDS is organised into regional sections for the different parts of the world, and there is a European Section of the MDS (MDS-ES), in charge of running educational programs on movement disorders in this region. The MDS-ES and the EAN obviously share common objectives to improve by all possible means the knowledge and management of movement disorders. During the last decade, MDS-ES and the past EFNS have worked together synergistically in order to avoid competition and duplications of efforts and meetings and this collaboration has proven to be very successful.

As the current chair of the MDS-ES, I am strongly supporting the concept that this previous agreement between the EFNS and the MDS-ES serves as a model for establishing collaboration between the EAN and the MDS-ES for the future. Our two societies are currently working on this project and I am quite optimistic about its outcome. Overall, its general principle is that the MDS-ES would run movement disorders sessions within the annual congresses of the EAN, thus avoiding wasting time and money for an independent parallel MDS-ES annual congress. Apart from the annual meetings, this agreement would also encourage and reinforce joint educational initiatives and funding strategies for important programs toward training doctors, neurologists, allied health professionals and patients with movement disorders in different parts of Europe.

GLL: What is your view on the future of the educational grants for young neurologists? Can you see possible co-operation between the MDS and the EAN in this field?

OR: There are many key educational and training domains where the MDS-ES and the EAN could and should cooperate to improve the knowledge and management of movement disorders in Europe. A variety of initiatives can be envisioned, including continuing and expending existing ones (such as educational grants to allow candidates to visit and stay long enough to learn in internationally recognised European reference centres for Movement Disorders) or organising new ones (like for example implementing focused workshops or local teaching courses, developing e-learning …) in order to:

– raise the interest of young neurologists for movement disorders
– improve diagnosis and treatment of movement disorders among physicians and general neurologists, focusing not only on common movement disorders like Parkinson’s disease, but also on less frequent but important ones like tremor, dystonia, Huntington disease, tics, atypical parkinsonism, myoclonus and others, and encouraging transversal disciplines within neurology like neuro-epidemiology, neuro-imaging, neuro-physiology, neuro-pharmacology and others
– encourage teaching basic neurosciences to clinicians and vice-versa
– offer specific opportunities to underserved areas within Europe (e.g. Eastern European countries) or out of Europe (e.g. Africa for example)
– train allied health professionals (physiotherapists, speech therapists, psychologists, occupational therapists, etc…) as a multidisciplinary approach is becoming more and more important to improve the care of patients with movement disorders and neurodegenerative disorder.

GLL: Can you share with our readers your vision on how Neuropenews can help strengthen the EAN’s identity?

OR: I see Neuropenews as a modern, flexible and efficient tool to raise people´s awareness and understanding of the EAN initiatives and make them feeling to belong to the same academic European community. It should allow publishing the ongoing and future strategic, educational and research activities of the EAN within the different sub-specialities of neurology within European countries and across Europe. Exchanging past experiences and reporting on previously obtained successful stories should allow others to build on achievements, facilitating thus future accomplishments. It seems to me that Neuropenews should be an excellent instrument to improve communication and exchanges within neurology and related scientific and medical specialities.

GLL: You are Professor of Clinical Pharmacology, but since the beginning of your scientific career you have been very near to neurology, as I have personally witnessed. Could you tell our younger readers something more about your scientific career and what you considered its “turning points”?

OR: I am a neurologist by training and I continue, as a clinician, to diagnose, follow-up and treat patients with movement disorders at the department of neurology of the Toulouse University Hospital. I feel this as a mandatory activity to keep a close contact with patients’ needs. But besides this long-lasting and sustained medical practice, I have developed early in my academic career a special curiosity and interest for physiology and pharmacology, in order to better understand the mechanisms causing movement disorders and explaining the effects of their treatments. For that purpose, I worked in basic sciences and got a PhD in experimental therapeutics after my MD, in the mid-eighties. My ambition was to optimise the translation of pre-clinical discoveries into clinical practice, based on objective methods rather than empirical experience, which was the rule at this time. I therefore logically moved from animal models into clinical trials and clinical neuropharmacology, a field that was quite underdeveloped in movement disorders in these times. I was fortunate enough within the last 3 decades in contributing to bringing to the market a number of new dopaminergic antiparkinsonian medications including dopamine agonists like ropinirole, pramipexole or rotigotine, MAO-B inhibitors like rasagiline and COMT inhibitors like entacapone.

I was excited, and still feel so, to test scientifically in patients the effects of new drugs on motor symptoms, to work with new concepts that moved from dopamine to non-dopamine targets, from oral to non-oral drug delivery and from short-term symptomatic management to long-term “disease modification” of neurodegenerative disorders. Such activity in clinical neuropharmacology is a lot of fun because it requires close collaborations between basic scientists, clinicians, methodologists and pharmaceutical companies at the international level. The field has dramatically expended as novel approaches have emerged to drive future progresses, based not only on pharmacological innovation, but also on genetics, new techniques and non-pharmacological interventions using devices, surgery, biotherapies…
It has been a major milestone in my career to realise how patients with movement disorders were disabled by a broad spectrum of non-motor symptoms, including sleep problems, dementia, autonomic dysfunction, pain, mood and behavioural modifications and others. It was a shock when we realised how long and how much we had ignored these major aspects of “movement disorders” that we did not really know how to treat, and to admit that such symptoms occurred long before motor symptoms could be detected, leading to the concept of “pre-motor” or even “pre-symptomatic” phases of these disorders, opening the field for future truly preventive goals. I was also astonished how long it took before neurologists admitted the reality and the importance of troublesome drug-induced side effects like daytime sleepiness and impulse control disorders. All these events expended substantially the field of neuropharmacology of “movement disorders”, encouraging the development of new models, new techniques, new collaborations, new outcomes and new designs for clinical trials.
It has been a refreshing experience for me to participate into the demonstration of new unexpected properties of “old” drugs, like for example the anti-dyskinetic properties of amantadine for the treatment of L-DOPA-induced dyskinesia. I should not underestimate here the importance of other therapeutic issues I have been interested in, like for example defining the best possible strategies to manage on the long-term patients with movement disorders. This means not simply looking at the short-term benefit-risk ratio of one single therapeutic intervention but rather focusing on the different possible combinations of different pharmacological and non-pharmacological interventions, including drugs, physiotherapy and surgery. Should we use them together simultaneously or sequentially? Should we start patients with Parkinson’s disease on L-DOPA early or late? When is physiotherapy most useful? When is the most appropriate time to offer deep brain stimulation to our patients? Such questions raise complex practical, methodological and economic problems. These are beyond the scope of regulatory Phase III trials, classically sponsored by private drug companies, and require novel public network organisation and funding, with appropriate solutions coming probably at the European level. I also hope that the time will come when the progresses of pharmaco-genetics will allow offering patients with movement disorders a “personalized” approach, on the model of what has been successfully achieved in other medical areas like thrombosis or cancer. Finally, I would also like to emphasise at this point the importance of applying to the field of movement disorders and neurology in general other important but still under-used pharmacological approaches, including pharmaco-epidemiology to better understand the diversity of patients’ care in different European countries, and learn from such discrepancies how to improve our practice, and pharmaco-economy to encourage novel public health perspective, assess how resources are used and allocated to treat movement disorders in Europe and then be optimised. And I hope that all these exciting opportunities will raise the interest of many young neurologists!

Interview with Olivier Rascol was last modified: November 12th, 2018 by Editor
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