Neural basis of impulse control behaviours in Parkinson’s disease
Up to 20% of patients with Parkinson’s disease (PD) develop impulse control behaviours (ICBs) on dopaminergic therapy, particularly on dopamine receptor agonists. Impulsive behaviour can include pathological gambling, shopping, hypersexuality, binge eating and punding, all of which can have a debilitating impact on patients and their families. Treatment often consists of reducing the dose of dopamine agonists, significantly limiting optimal therapy of motor symptoms in PD.
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