Vagal nerve stimulation may improve post-stroke motor recovery
The Vagus Nerve Stimulation (VNS) may promote reorganization of motor networks via engaging a variety of molecular and neuronal mechanisms through ascending neuromodulatory systems. A recently published review from Frontiers in Neuroscience (N.D. Engineer et al. Targeted Vagus nerve stimulation for rehabilitation after stroke, Front Neurosci. 2019, 29;13:280) has laid out how recent experimental and clinical studies are providing increasing evidence for a beneficial effect of vagus nerve stimulation for the motor recovery after stroke of both, ischemic and hemorrhagic origin. Two multi-site, randomized controlled pilot trials have suggested that when paired with neurorehabilitation, VNS stimulation may generate temporally precise neuromodulatory feedback within the synaptic eligibility trace and may hence, drive synaptic plasticity.
Please continue here.