eanpages
  • General interest
    • All Executive Page Paper of the Month EAN News EAN Congress news COVID-19 Interviews
      EAN News

      Become a Certified Leader of European Neurology with the new EAN Leadership Programme

      January 24, 2023

      EAN News

      COVID-19 Research Round-Up: Literature reviews – January 2023

      January 17, 2023

      EAN News

      COVID-19 Research Round-Up: Case Series/Case Reports – January 2023

      January 17, 2023

      EAN News

      COVID-19 Research Round-Up: Cross-Sectional Case Control Studies – January 2023

      January 17, 2023

      Executive Page

      Executive Page: Submit, register, and join us for EAN 2023

      December 5, 2022

      Executive Page Dear EAN members, dear friends, It is my pleasure to give you an update on behalf of the EAN Scientific Committee following a busy year since my appointment as chair. It has been a privilege to be so deeply involved in the scientific activities of the EAN and to work closely with an amazing community of people who are so dedicated to the advancement of neurology. One of the strongest threads within that community is the EAN’s group of Scientific Panels, which are often referred to as the organisation’s ‘scientific backbone’. The panels have a hand in everything the EAN does from a scientific point of view, including coordinating clinical research, disseminating good practice, assisting in planning the EAN annual congress, supporting the EAN’s educational efforts, and producing guidelines that assist neurologists in daily practice. All of this work requires a considerable amount of oversight, and this is why each panel is run by its own Management Group, elected by the panel members. Being a part of one of these Management Groups (PDF) is an opportunity to play a direct part in determining the direction of scientific progress within Europe, and I am excited to say that the call for applications to stand for election will be announced in September. All panel members and EAN individual members are eligible to apply to be candidates, with the vote being held among the existing panel members in autumn. I would like to urge every neurologist with a passion for the scientific future of their special area of interest to consider standing for election to the relevant Management Group and to look out for the call for applications later this month. I can tell you from personal experience that fulfilling a role such as this within the structure of the EAN is a fascinating and extremely rewarding experience. The chance to take on such a unique leadership position should not be missed! The most satisfying aspect of being involved in the EAN’s organisational structure is surely seeing all the hard work and planning come to fruition when a small idea evolves into a newly launched project. One such example is the 1st EAN Science School, taking place in Salzburg next March. The idea of the Science School is to offer early career neurologists with an interest in translational research a new avenue for learning about basic pathomechanisms of neurological disorders. Application for this very first edition, on ‘Pathophysiology of disorders of the nervous system’, closed last week and we have been delighted with the level of interest. It was a pleasure to be part of the task force in charge of planning this new project and I look forward to seeing it officially transferred to the hands of the Scientific Committee after a successful event and evaluation in spring. Of our ongoing activities, one of the most significant is the EAN Neuro-covid Registry, which aims to collate epidemiological data on neurological manifestations in patients with COVID-19 infection reported by neurologists in outpatient services, emergency rooms, and hospital departments. We currently have 1,542 patients entered in the database, from 35 centres across 23 countries. So far, 29 patients have been followed for 12 months and 387 have completed the 6-months follow up. This is a decent start, but I would like to strongly encourage EAN members and their institutions to get involved and contribute cases to what will become an invaluable resource for neurologists and clinicians to improve care for Covid-19 patients. Finally, I would like share a word on a forthcoming collaboration between EAN and the Human Brain Project in December, that I think will interest a lot of EAN members. The EAN-EBRAINS joint workshop on ‘The future of medical data sharing in clinical neurosciences’ will be a three-day virtual event that aims to discuss issues and challenges associated with data sharing in Europe, from ethics to data safety and privacy, including those specific to data federation, such as the development and validation of federated algorithms. The whole workshop is completely free of charge and registration is open until 25 November, so please check out the details and sign up! I wish you all a healthy and pleasant autumn and I look forward to updating you again. Best wishes Thomas Berger Chair of the EAN Scientific Committee

      Executive Page: New guideline prioritisation process begins setting path for next two years

      November 1, 2022

      Executive Page EAN Secretary General, 2022. Tony Marson, Liverpool UK.

      Executive Page: More reasons than ever to renew your EAN membership

      October 11, 2022

      Executive Page Head and shoulders portrait photo of Irena Rektorova, in colourful dress

      Executive Page: Challenge of maintaining high standards is a privilege says incoming Education Committee Chair

      September 1, 2022

      Paper of the Month

      Research Paper of the Month: Intensive blood pressure control after endovascular thrombectomy for acute ischaemic stroke (ENCHANTED2/MT)

      January 1, 2023

      Paper of the Month

      COVID-19 Paper of the Month: The decline in stroke hospitalization due to COVID-19 is unrelated to COVID-19 intensity

      January 1, 2023

      Paper of the Month

      Research Paper of the Month: Lecanemab in Early Alzheimer’s Disease

      December 5, 2022

      Paper of the Month

      Covid-19 Paper of the Month: Incidence of Epilepsy and Seizures Over the First 6 Months After a COVID-19 Diagnosis

      December 5, 2022

      EAN News

      Become a Certified Leader of European Neurology with the new EAN Leadership Programme

      January 24, 2023

      EAN News

      COVID-19 Research Round-Up: Literature reviews – January 2023

      January 17, 2023

      EAN News

      COVID-19 Research Round-Up: Case Series/Case Reports – January 2023

      January 17, 2023

      EAN News

      COVID-19 Research Round-Up: Cross-Sectional Case Control Studies – January 2023

      January 17, 2023

      EAN Congress news

      EAN launches new ‘Congress Spin-Off with Masterclasses’ event, with first edition in March

      January 10, 2023

      EAN Congress news

      Video Interview: Dementia & Cognitive Disorders Panel Co-Chairs

      September 8, 2022

      EAN Congress news

      EAN 2023 – Join us in Budapest on July 1-4

      September 1, 2022

      EAN Congress news

      Special EAN issue of BrainMag features reports on EAN 2022 and more

      August 30, 2022

      COVID-19

      COVID-19 Research Round-Up: Literature reviews – January 2023

      January 17, 2023

      COVID-19

      COVID-19 Research Round-Up: Case Series/Case Reports – January 2023

      January 17, 2023

      COVID-19

      COVID-19 Research Round-Up: Cross-Sectional Case Control Studies – January 2023

      January 17, 2023

      COVID-19

      COVID-19 Paper of the Month: The decline in stroke hospitalization due to COVID-19 is unrelated to COVID-19 intensity

      January 1, 2023

      Interviews

      Video Interview: Dementia & Cognitive Disorders Panel Co-Chairs

      September 8, 2022

      Interviews

      Video Interview: Sleep-Wake Panel Co-Chair, Dr. Evelina Pajediene

      July 28, 2022

      Interviews

      Video: EAN supports World Brain Day

      July 19, 2022

      Interviews

      Video Interview: European Journal of Neurology Award winner, Dr. Jonathan Coutinho

      July 18, 2022

  • Academic/Scientific
    • All Breaking news Neurology updates Scientific committee reports Scientific panels reports Eur J Neurol Top 10 Articles Scientific Corner
      EAN News

      COVID-19 Research Round-Up: Literature reviews – January 2023

      January 17, 2023

      EAN News

      COVID-19 Research Round-Up: Case Series/Case Reports – January 2023

      January 17, 2023

      EAN News

      COVID-19 Research Round-Up: Cross-Sectional Case Control Studies – January 2023

      January 17, 2023

      EAN News

      Impact of Burnout on Neurology Residents and Research Fellows in Europe

      December 23, 2022

      Breaking news

      COVID-19 Breaking News: Meta-analyses/systematic reviews – November 2022

      November 8, 2022

      Breaking news

      COVID-19 Breaking News: Cross-Sectional Case Control Studies – November 2022

      November 8, 2022

      Breaking news

      COVID-19 Breaking News: Miscellaneous – November 2022

      November 7, 2022

      Breaking news

      COVID-19 Breaking News: Observational Studies – Prospective Longitudinal Cohort – November 2022

      November 7, 2022

      Neurology updates

      Performance of the 2017 and 2010 Revised McDonald Criteria in Predicting MS Diagnosis After a Clinically Isolated Syndrome – A MAGNIMS Study

      September 26, 2022

      Neurology updates

      Relapse-independent disability worsening plays a relevant role in every disease phase of MS

      September 26, 2022

      Neurology updates

      Epstein-Barr virus infection is a major risk factor for the development of multiple sclerosis

      September 26, 2022

      Neurology updates

      Glymphatic system impairment may contribute to multiple sclerosis pathology

      September 23, 2022

      Scientific committee reports

      Scientific Committee Snapshot: Didier Leys

      April 1, 2020

      Scientific committee reports

      Scientific Committee Snapshot: Rigmor Hojland

      February 26, 2020

      Scientific committee reports

      Scientific Committee Snapshot: Christian Enzinger

      December 1, 2019

      Scientific committee reports

      Scientific Committee Snapshot: Maurizio Leone

      November 1, 2019

      Scientific panels reports

      Highlights from the World Muscle Society annual meeting, chosen by the Scientific Panel on Muscle and NMJ Disorders

      November 2, 2022

      Scientific panels reports

      Coma and DOC Panel Update (May-June): news from the EAN Virtual Congress, personalized pain assessment, NIRS-EEG and machine learning to predict outcomes, prevalence of swallowing disorders and new multimodal predictive algorithms.

      August 11, 2020

      Scientific panels reports

      Statement of the EAN Sleep-Wake-Panel

      June 3, 2020

      Scientific panels reports

      Rare Neurological Diseases in the COVID-19 era: Suggestions for information to patients and caregivers

      May 13, 2020

      Eur J Neurol

      Video Interview: European Journal of Neurology Award winner, Dr. Jonathan Coutinho

      July 18, 2022

      Eur J Neurol

      EAN NeuroCOVID-19 Task Force position paper on COVID-19 vaccination hesitancy among people with chronic neurological disorders

      May 2, 2022

      Eur J Neurol

      European Journal of Neurology welcomes new associate editors

      December 13, 2021

      Eur J Neurol

      New European guideline and expert statements on the management of narcolepsy in adults and children

      June 30, 2021

      Top 10 Articles

      EAN is proud to announce the 2020 Virtual Master Classes Christmas Special

      November 13, 2020

      Top 10 Articles

      EUROPEAN JOURNAL OF NEUROLOGY – TOP 15 ARTICLES 2018

      February 1, 2019

      Top 10 Articles

      Interview with Prof. Patrick Cras – UEMS Section of Neurology (SN)

      February 3, 2018

      Top 10 Articles

      Interview with Mr. Bertrand Daval and Mrs. Nathalie Paulus

      February 3, 2018

      Scientific Corner

      Join the EAN Guideline Workshop on 24 June!

      May 13, 2022

      Scientific Corner

      First EAN Science School proves a hit in Salzburg

      April 1, 2022

      Scientific Corner

      Invitation to the EAN-EBRAINS Joint Workshop on ‘The Future of Medical Data Sharing in Clinical Neurosciences’

      July 2, 2021

      Scientific Corner

      1st EAN Science School, 26-29 March 2022: “Pathophysiology of disorders of the nervous system”

      June 18, 2021

  • Educational
    • All eLearning Student Corner E-Brain Grand Rounds Resident and Research Fellows Fellowship reports Education corner
      Student Corner

      Application for the Student Teaser Fellowship 2023 NOW OPEN

      February 1, 2023

      EAN News

      Become a Certified Leader of European Neurology with the new EAN Leadership Programme

      January 24, 2023

      Fellowship reports

      Clinical Fellowship Reports 2022: Stockholm & Erlangen

      January 18, 2023

      Student Corner Illustration of a vertical pencil point on a blue background, with a yellow light bulb above it

      Students’ Corner: What neurology taught me in 2022

      January 17, 2023

      eLearning Illustration of two people holding an award between them and jumping in the air in a celebratory pose

      Learn with the eanCampus and win free EAN congress registration!

      January 12, 2023

      eLearning

      Kick off 2023 with highlights on the eanCampus

      January 10, 2023

      eLearning

      December Highlights on the eanCampus!

      December 5, 2022

      eLearning

      November Highlights on the eanCampus!

      November 4, 2022

      Student Corner

      Application for the Student Teaser Fellowship 2023 NOW OPEN

      February 1, 2023

      Student Corner Illustration of a vertical pencil point on a blue background, with a yellow light bulb above it

      Students’ Corner: What neurology taught me in 2022

      January 17, 2023

      Student Corner

      Student Teaser Fellowship reports 2022 – Karlsbad, Zagreb & Salzburg

      January 10, 2023

      Student Corner

      Student Teaser Fellowship reports 2022 – Salzburg, Ramat Gan, & Rostock

      December 30, 2022

      E-Brain

      ebrain May update: new website and podcast series

      May 1, 2021

      E-Brain

      EBRA launches 3rd call for clusters

      May 1, 2020

      E-Brain

      News from ebrain

      February 28, 2020

      E-Brain

      ebrain to host the 2019 Neurology Formative Test Questions, from 15 April to 26 May

      April 1, 2019

      Grand Rounds

      eBrain: virtual case report from Belgium

      October 2, 2017

      Grand Rounds

      Free access to Ebrain for EAN members

      July 1, 2016

      Grand Rounds

      Ebrain granted Royal College of Physicians (UK) CPD/CME accreditation

      July 1, 2016

      Grand Rounds

      ebrain session of the month: neuromuscular junction

      February 1, 2016

      Resident and Research Fellows

      Become a Certified Leader of European Neurology with the new EAN Leadership Programme

      January 24, 2023

      Resident and Research Fellows

      13th Regional Teaching Course in Sub-Saharan Africa – Report

      January 12, 2023

      Resident and Research Fellows Close up photo of a Black graduation cap and yellow tassel

      European Board Examination in Neurology – Reasons to take it and how to contribute

      January 12, 2023

      Resident and Research Fellows

      Third round of pairs matched in EAN Mentorship Programme

      January 12, 2023

      Fellowship reports

      Clinical Fellowship Reports 2022: Stockholm & Erlangen

      January 18, 2023

      Fellowship reports

      Student Teaser Fellowship reports 2022 – Karlsbad, Zagreb & Salzburg

      January 10, 2023

      Fellowship reports

      Clinical Fellowship Reports 2022: Bern & Prague

      December 30, 2022

      Fellowship reports

      Student Teaser Fellowship reports 2022 – Salzburg, Ramat Gan, & Rostock

      December 30, 2022

      Education corner

      Application for the Student Teaser Fellowship 2023 NOW OPEN

      February 1, 2023

      Education corner

      Become a Certified Leader of European Neurology with the new EAN Leadership Programme

      January 24, 2023

      Education corner

      Clinical Fellowship Reports 2022: Stockholm & Erlangen

      January 18, 2023

      Education corner

      13th Regional Teaching Course in Sub-Saharan Africa – Report

      January 12, 2023

  • Other News
    • All EAN Staff Grant opportunities News from EAN member societies EBC EFNA News in general Patients societies reports Surveys Forum
      EAN Staff Composite image consisting of two chest-height portraits ide-by-side

      EAN Head Office Profiles: Katina & Robertina

      February 2, 2023

      Other News Portrait photo of Dr Ralph Sacco, former president of the American Academy of Neurology, in his office, wearing a white lab coat

      In Memoriam: Dr Ralph Sacco, former president of the American Academy of Neurology

      January 19, 2023

      EAN Staff

      EAN Head Office Profiles: Magda & Mira

      December 29, 2022

      News in general

      Registration now open for the launch event of the RETHINKING Alzheimer’s disease White Paper

      December 24, 2022

      EAN Staff Composite image consisting of two chest-height portraits ide-by-side

      EAN Head Office Profiles: Katina & Robertina

      February 2, 2023

      EAN Staff

      EAN Head Office Profiles: Magda & Mira

      December 29, 2022

      EAN Staff

      EAN Head Office Profiles: Peter & Nadine

      November 24, 2022

      EAN Staff

      EAN Head Office Profiles: Katharina & Rena

      October 31, 2022

      Grant opportunities

      1st EAN Science School, 26-29 March 2022: “Pathophysiology of disorders of the nervous system”

      June 18, 2021

      Grant opportunities

      European Commission: Innovation and novelty in medical devices and in vitro diagnostic devices; towards common concepts of innovation-related risk assessments

      November 1, 2019

      Grant opportunities

      GBS|CIDP Foundation International 2020 Research Grant Opportunity

      October 29, 2019

      Grant opportunities

      The Clinical Fellowship application deadline is approaching

      October 1, 2019

      News from EAN member societies

      14 June: Special publication celebrates 10 years of the European Working Group of People with Dementia

      August 2, 2022

      News from EAN member societies

      14 June: Alzheimer Europe hosts European Parliament Lunch Debate examining EU and WHO policies on neurological conditions

      August 2, 2022

      News from EAN member societies

      22 June: Alzheimer Europe invites applications for its new Anti-Stigma Award

      August 2, 2022

      News from EAN member societies

      Alzheimer Europe publishes new reports on ‘sex, gender and sexuality in the context of dementia’, and ‘dementia-inclusive initiatives and communities’

      April 5, 2022

      EBC

      Connecting brains for the future: Brain Innovation Days 2022

      November 23, 2022

      EBC

      Final programme available for Brain Innovation Days – Register now!

      September 22, 2022

      EBC

      EPICLUSTER Final Meeting – shaping the future of epilepsy research in Europe

      August 26, 2022

      EBC

      Registration open for Brain Innovation Days 2022

      August 19, 2022

      EFNA

      OneNeurology European Summit underlines urgent need to prioritise neurology and drive change

      December 31, 2021

      EFNA

      EFNA launch eLearning Platform for neurology advocates

      February 1, 2021

      EFNA

      ‘Me and My Brain’ – Art Competition winners announced!

      February 1, 2021

      EFNA

      Survey on the impact of COVID-19 on neurology service delivery

      November 1, 2020

      News in general

      Registration now open for the launch event of the RETHINKING Alzheimer’s disease White Paper

      December 24, 2022

      News in general

      EAN lecture at the International Neuro-Urology Society annual congress 2022

      May 25, 2022

      News in general

      EPA-EAN Joint Symposium: ‘Etiology and Treatment of the Long Covid-19 Syndrome’ and other highlights at the 30th European Congress of Psychiatry

      May 25, 2022

      News in general

      Organise an EAN-Day or EAN Regional Teaching Course in your Country!

      May 17, 2022

      Patients societies reports

      News from Alzheimer Europe

      March 2, 2020

      Patients societies reports

      News from the WHO

      January 9, 2020

      Patients societies reports

      News from EFIC and the European Pain Forum

      January 3, 2020

      Patients societies reports

      News from EFIC and the European Pain Forum

      January 2, 2020

      Surveys

      Help EAN contribute towards the development of a European Pain Research strategy

      December 5, 2022

      Surveys

      Survey: management of covert brain infarction

      October 29, 2021

      Surveys

      Driving with an intracranial tumor

      July 13, 2020

      Surveys

      SURVEY: Driving with an intracranial tumor

      June 25, 2020

      Forum

      Call for Applications: e-Learning Platform Editor-in-Chief

      August 4, 2020

      Forum

      Neurological News from Denmark VI – the land of the 2nd EAN congress 2016: Pain Research in Denmark from a neurological perspective

      April 1, 2016

      Forum

      Neurological News from Denmark V – the land of the 2nd EAN congress 2016: Clinical Dementia Research in Denmark

      March 1, 2016

      Forum

      Updated recommendations to minimise the risk of the rare brain infection PML with Tysabri – Comment to EMA recommendation

      March 1, 2016

  • EAN
  • Congress 2023
  • EANpages
  • EAN Campus
  • Eur J Neurol
  • Virtual Congress

eanpages

  • General interest
    • All Executive Page Paper of the Month EAN News EAN Congress news COVID-19 Interviews
      EAN News

      Become a Certified Leader of European Neurology with the new EAN Leadership Programme

      January 24, 2023

      EAN News

      COVID-19 Research Round-Up: Literature reviews – January 2023

      January 17, 2023

      EAN News

      COVID-19 Research Round-Up: Case Series/Case Reports – January 2023

      January 17, 2023

      EAN News

      COVID-19 Research Round-Up: Cross-Sectional Case Control Studies – January 2023

      January 17, 2023

      Executive Page

      Executive Page: Submit, register, and join us for EAN 2023

      December 5, 2022

      Executive Page Dear EAN members, dear friends, It is my pleasure to give you an update on behalf of the EAN Scientific Committee following a busy year since my appointment as chair. It has been a privilege to be so deeply involved in the scientific activities of the EAN and to work closely with an amazing community of people who are so dedicated to the advancement of neurology. One of the strongest threads within that community is the EAN’s group of Scientific Panels, which are often referred to as the organisation’s ‘scientific backbone’. The panels have a hand in everything the EAN does from a scientific point of view, including coordinating clinical research, disseminating good practice, assisting in planning the EAN annual congress, supporting the EAN’s educational efforts, and producing guidelines that assist neurologists in daily practice. All of this work requires a considerable amount of oversight, and this is why each panel is run by its own Management Group, elected by the panel members. Being a part of one of these Management Groups (PDF) is an opportunity to play a direct part in determining the direction of scientific progress within Europe, and I am excited to say that the call for applications to stand for election will be announced in September. All panel members and EAN individual members are eligible to apply to be candidates, with the vote being held among the existing panel members in autumn. I would like to urge every neurologist with a passion for the scientific future of their special area of interest to consider standing for election to the relevant Management Group and to look out for the call for applications later this month. I can tell you from personal experience that fulfilling a role such as this within the structure of the EAN is a fascinating and extremely rewarding experience. The chance to take on such a unique leadership position should not be missed! The most satisfying aspect of being involved in the EAN’s organisational structure is surely seeing all the hard work and planning come to fruition when a small idea evolves into a newly launched project. One such example is the 1st EAN Science School, taking place in Salzburg next March. The idea of the Science School is to offer early career neurologists with an interest in translational research a new avenue for learning about basic pathomechanisms of neurological disorders. Application for this very first edition, on ‘Pathophysiology of disorders of the nervous system’, closed last week and we have been delighted with the level of interest. It was a pleasure to be part of the task force in charge of planning this new project and I look forward to seeing it officially transferred to the hands of the Scientific Committee after a successful event and evaluation in spring. Of our ongoing activities, one of the most significant is the EAN Neuro-covid Registry, which aims to collate epidemiological data on neurological manifestations in patients with COVID-19 infection reported by neurologists in outpatient services, emergency rooms, and hospital departments. We currently have 1,542 patients entered in the database, from 35 centres across 23 countries. So far, 29 patients have been followed for 12 months and 387 have completed the 6-months follow up. This is a decent start, but I would like to strongly encourage EAN members and their institutions to get involved and contribute cases to what will become an invaluable resource for neurologists and clinicians to improve care for Covid-19 patients. Finally, I would like share a word on a forthcoming collaboration between EAN and the Human Brain Project in December, that I think will interest a lot of EAN members. The EAN-EBRAINS joint workshop on ‘The future of medical data sharing in clinical neurosciences’ will be a three-day virtual event that aims to discuss issues and challenges associated with data sharing in Europe, from ethics to data safety and privacy, including those specific to data federation, such as the development and validation of federated algorithms. The whole workshop is completely free of charge and registration is open until 25 November, so please check out the details and sign up! I wish you all a healthy and pleasant autumn and I look forward to updating you again. Best wishes Thomas Berger Chair of the EAN Scientific Committee

      Executive Page: New guideline prioritisation process begins setting path for next two years

      November 1, 2022

      Executive Page EAN Secretary General, 2022. Tony Marson, Liverpool UK.

      Executive Page: More reasons than ever to renew your EAN membership

      October 11, 2022

      Executive Page Head and shoulders portrait photo of Irena Rektorova, in colourful dress

      Executive Page: Challenge of maintaining high standards is a privilege says incoming Education Committee Chair

      September 1, 2022

      Paper of the Month

      Research Paper of the Month: Intensive blood pressure control after endovascular thrombectomy for acute ischaemic stroke (ENCHANTED2/MT)

      January 1, 2023

      Paper of the Month

      COVID-19 Paper of the Month: The decline in stroke hospitalization due to COVID-19 is unrelated to COVID-19 intensity

      January 1, 2023

      Paper of the Month

      Research Paper of the Month: Lecanemab in Early Alzheimer’s Disease

      December 5, 2022

      Paper of the Month

      Covid-19 Paper of the Month: Incidence of Epilepsy and Seizures Over the First 6 Months After a COVID-19 Diagnosis

      December 5, 2022

      EAN News

      Become a Certified Leader of European Neurology with the new EAN Leadership Programme

      January 24, 2023

      EAN News

      COVID-19 Research Round-Up: Literature reviews – January 2023

      January 17, 2023

      EAN News

      COVID-19 Research Round-Up: Case Series/Case Reports – January 2023

      January 17, 2023

      EAN News

      COVID-19 Research Round-Up: Cross-Sectional Case Control Studies – January 2023

      January 17, 2023

      EAN Congress news

      EAN launches new ‘Congress Spin-Off with Masterclasses’ event, with first edition in March

      January 10, 2023

      EAN Congress news

      Video Interview: Dementia & Cognitive Disorders Panel Co-Chairs

      September 8, 2022

      EAN Congress news

      EAN 2023 – Join us in Budapest on July 1-4

      September 1, 2022

      EAN Congress news

      Special EAN issue of BrainMag features reports on EAN 2022 and more

      August 30, 2022

      COVID-19

      COVID-19 Research Round-Up: Literature reviews – January 2023

      January 17, 2023

      COVID-19

      COVID-19 Research Round-Up: Case Series/Case Reports – January 2023

      January 17, 2023

      COVID-19

      COVID-19 Research Round-Up: Cross-Sectional Case Control Studies – January 2023

      January 17, 2023

      COVID-19

      COVID-19 Paper of the Month: The decline in stroke hospitalization due to COVID-19 is unrelated to COVID-19 intensity

      January 1, 2023

      Interviews

      Video Interview: Dementia & Cognitive Disorders Panel Co-Chairs

      September 8, 2022

      Interviews

      Video Interview: Sleep-Wake Panel Co-Chair, Dr. Evelina Pajediene

      July 28, 2022

      Interviews

      Video: EAN supports World Brain Day

      July 19, 2022

      Interviews

      Video Interview: European Journal of Neurology Award winner, Dr. Jonathan Coutinho

      July 18, 2022

  • Academic/Scientific
    • All Breaking news Neurology updates Scientific committee reports Scientific panels reports Eur J Neurol Top 10 Articles Scientific Corner
      EAN News

      COVID-19 Research Round-Up: Literature reviews – January 2023

      January 17, 2023

      EAN News

      COVID-19 Research Round-Up: Case Series/Case Reports – January 2023

      January 17, 2023

      EAN News

      COVID-19 Research Round-Up: Cross-Sectional Case Control Studies – January 2023

      January 17, 2023

      EAN News

      Impact of Burnout on Neurology Residents and Research Fellows in Europe

      December 23, 2022

      Breaking news

      COVID-19 Breaking News: Meta-analyses/systematic reviews – November 2022

      November 8, 2022

      Breaking news

      COVID-19 Breaking News: Cross-Sectional Case Control Studies – November 2022

      November 8, 2022

      Breaking news

      COVID-19 Breaking News: Miscellaneous – November 2022

      November 7, 2022

      Breaking news

      COVID-19 Breaking News: Observational Studies – Prospective Longitudinal Cohort – November 2022

      November 7, 2022

      Neurology updates

      Performance of the 2017 and 2010 Revised McDonald Criteria in Predicting MS Diagnosis After a Clinically Isolated Syndrome – A MAGNIMS Study

      September 26, 2022

      Neurology updates

      Relapse-independent disability worsening plays a relevant role in every disease phase of MS

      September 26, 2022

      Neurology updates

      Epstein-Barr virus infection is a major risk factor for the development of multiple sclerosis

      September 26, 2022

      Neurology updates

      Glymphatic system impairment may contribute to multiple sclerosis pathology

      September 23, 2022

      Scientific committee reports

      Scientific Committee Snapshot: Didier Leys

      April 1, 2020

      Scientific committee reports

      Scientific Committee Snapshot: Rigmor Hojland

      February 26, 2020

      Scientific committee reports

      Scientific Committee Snapshot: Christian Enzinger

      December 1, 2019

      Scientific committee reports

      Scientific Committee Snapshot: Maurizio Leone

      November 1, 2019

      Scientific panels reports

      Highlights from the World Muscle Society annual meeting, chosen by the Scientific Panel on Muscle and NMJ Disorders

      November 2, 2022

      Scientific panels reports

      Coma and DOC Panel Update (May-June): news from the EAN Virtual Congress, personalized pain assessment, NIRS-EEG and machine learning to predict outcomes, prevalence of swallowing disorders and new multimodal predictive algorithms.

      August 11, 2020

      Scientific panels reports

      Statement of the EAN Sleep-Wake-Panel

      June 3, 2020

      Scientific panels reports

      Rare Neurological Diseases in the COVID-19 era: Suggestions for information to patients and caregivers

      May 13, 2020

      Eur J Neurol

      Video Interview: European Journal of Neurology Award winner, Dr. Jonathan Coutinho

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Amyotrophic Lateral Sclerosis and COVID-19 – Recommendations to patients and caregivers

April 15, 2020

7. April 2020

In patients with Amyotrophic Lateral Sclerosis (ALS), the impact of respiratory infections is expected to be more serious than in the general population, due to the weakness of the respiratory muscles and limitations in coughing (1-4). ALS patients with impaired respiratory function and/or rapid clinical deterioration are considered a high risk population for COVID-19 (5), even if no estimates in the different European countries are available.

ENCALS centres and the EAN panel on ALS and Frontotemporal Dementia are working together across countries to optimise support for our patients to protect them during this pandemic. National guidelines specifically concerning patients with ALS can be lacking and current regulations vary between different European countries. Available National guidelines are as follows, some of them addressing the general population:

  • Germany (6);
  • Ireland,
  • Italy: (7);
  • Poland: here (8); and here (9);
  • Portugal(10);
  • UK: MND Association (11); Government guidance (12); https://t.co/DsgD2EZnXr (13), with links to Trinity College Dublin (14); and here (15);
  • Switzerland: here (16); and here (17).

In the absence of guidelines specifically written to protect ALS patients and their families/ carers during the COVID-19 pandemic period, and acknowledging the various national regulations the consensus of a European Network for the Cure of ALS (ENCALS) and EAN ALS/FTD group of experts* is as follows:

Recommendations to ALS patients and family members/ carers, during the pandemic period of COVID-19 (SARS-CoV-2):

1st recommendation: Patients with ALS should be confined to their homes to prevent becoming infected. If living in a house with a backyard or in the countryside, going out inside the limits of the residence does not present a potential danger. It is advisable to avoid visitors, including family members/young children, even if they are without any symptoms. Hygiene should include more frequent hand washing with soap, avoiding hand-to-face contact (mouth, nose and eyes) and cleaning surfaces with detergent. (18) Carers should sneeze/ cough into the bent elbow or tissue, the tissues should be immediately discarded, and hands should be washed with soap. (18) Check the need to use masks by the patient/ family members/ others contacting the patient with the national authorities of your country and your physician (19-21). When using a mask, best practices should be followed about how to wear, remove, and dispose of it, and for hand hygiene after removal (21).

2nd recommendation: Identification of the principal carer: one principal carer should coordinate care provided to the patient. The principal carer should be someone who is always at home with the patient, in accordance with recommendation 1, to prevent being infected and transmitting the disease to the patient. Food and medication should be bought through online platforms or by ordering home delivery at local shops. Check the need to use masks with the national authorities of your country and the patient’s physician (19-21). When using a mask, best practices should be followed about how to wear, remove, and dispose of it, and for hand hygiene after removal (21).

3rd recommendation: Identification of additional carers: If possible, a second carer should be identified. If necessary, this carer should be available to cover for the principal carer, to prevent leaving the patient alone during unplanned periods, including due to quarantine/ isolation of the principal carer or others. Check the need to use masks with the national authorities of your country and the patient’s physician (19-21).

4rd recommendation: Unnecessary care/ Unavailable carer: If self sufficient but living alone without support, or if no carer is available although needed, the patient is advised to contact the ALS care centre, namely the coordinator or social worker who integrates the ALS team, to report the social situation so that support can be arranged if it becomes necessary.

5th recommendation: Outpatient care services: If support is provided by outpatient care services, a principal carer and an additional carer should be identified for each patient, limiting external contacts to avoid the risk of spreading the infection. This team, if not provided directly by the ALS team, should keep close contact with the ALS team to report on potential needs/ clinical deterioration/ respiratory emergency. The team should take all necessary measures to prevent possible transmission of the infection (20).

6th recommendation: In the case of an unplanned period of physical absence from the principal carer, and if no additional carer is available, the principal carer or the patient him/herself if capable, should report the situation to the ALS health providers, namely the social assistants integrating the ALS teams, local or national ALS association, palliative care team, homecare institution, local fireman association, or others that support community services.

7th recommendation: The principal carer is responsible for monitoring and providing, in the presence of functional limitations/ dependence and/or fronto-temporal dementia, for basic needs of the ALS patient including feeding/ hydration, administration of medication, respiratory support, mobilization and positioning, hygiene, comfort, physical and psychological wellbeing. The principal carer should also take care of him/herself, to maintain physical and psychological well-being. It is important to keep timetables, listen to calm and relaxing music, read books, engage in interesting activities at home, and have some periods for home physical exercise, if possible. Constant following of the news may be avoided.

8th recommendation: If in absolute need to go outside, both patient and carer/ family member should take the advised measures to minimise any risk of infection. Check the need to use masks by the patient, carer/ family member with the national authorities of your country and your physician (19-21). When arriving home, take off clothes (coats, bags, scarves, gloves, shoes) at the entrance to the house. Use disinfectant gel containing alcohol. Take off the mask, by only touching the elastic. Wash the hands with disinfectant products containing alcohol (18). If the patient uses walking aids/ wheelchair, these devices should be left also in the entrance of the house. The carer should help the patient. The walking aids/ wheelchair as well as other surfaces, including at the entrance, where the clothes from the outside are gathered, should be disinfected with detergents or products containing alcohol (22). Clothes should be washed with regular laundry detergent at temperatures above 40º Celsius.

9th recommendation:

If the patient develops fever, a non-productive cough, headache, muscle pain or dyspnoea, in the context of an external contact with someone who could be infected, the patient/ the principal carer should: 1- Stay calm. Do not go to the hospital or other healthcare centres. Stay at home; 2– Both use masks (18,21); 3- Measure the temperature and write down symptoms. Maintain a medication list, including dosing and administration times; 4- Contact the physician or medical team that follows you/ the patient, by phone, mail or available internet platforms.; 5- If no contact is available, phone the national healthcare line, or the COVID-19 line if available in your country. If nobody answers, ring again. Follow instructions. If the patient has already been adapted to non-invasive ventilation, a face mask without expiratory holes (or with the expiratory holes closed with tape), connected directly to a filter and to an expiratory piece should be used, to filter the expiratory air. In case of tracheostomy, a filter and the expiratory piece should be connected to the tube. If assistance is needed to remove bronchial secretions, for example by using a mechanical insufflator-exsufflator device, the carer should use FFP2 mask, goggles, gloves and gown, discard all biological material immediately and have a shower afterwards. As the coronavirus can be detected for at least 3 hours after aerosolization, mask and goggles should be used (22).

If the carer/family member is the one developing the symptoms: 1- Stay calm. Do not go to the hospital or other healthcare centres. Stay home; 2-Use masks (both) (18,21); 3- Record your symptoms as well as any symptoms that the patient may have. Have an actualized medication list; 4- Contact the additional carer so that he/she can be prepared to substitute if indicated when phoning the health providers; 5- Contact the COVID-19 line/ the national healthcare line as well as the ALS physician who follows the patient. Follow the instructions.

10th recommendation: In the case of respiratory decompensation, in ALS patients under home ventilatory support or initial respiratory symptoms in the context of ALS, the patient or the caregiver should contact the homecare/ palliative team/ caring ALS centre and inform the physician who regularly cares for the patient. If needed, call the 24/7 health support lines that may have been provided and link with the ALS care centre’ss support. Follow instructions.

11th recommendation: In case of respiratory emergency, first call the neurologist and respiratory physician in charge to finalize the required intervention. If needed, call the 24/7 health support lines that may have been provided and articulate it with the ALS care centres support.

12th recommendation: Keep well informed, by reading the news/ listening to reliable sources. Avoid fake news and misleading social media. Rely on official sources from your country. However limit the time that you spend listening to or reading the news. Be positive. This is a transitory period and it will end.

The present recommendations will be reviewed whenever pertinent, to adjust to the constant evolving evidence generated during the COVID-19 pandemic.

Andrà tutto bene. Vai ficar tudo bem. Wszystko będzie dobrze. Allt ska bli bra. Everything will be alright.

*ENCALS/ EAN expert panel

Susana Pinto (lead and draft of the recommendations)
Translational and Clinical Physiology Unit, Instituto de Medicina Molecular,
Faculty of Medicine, University of Lisbon
Lisbon, Portugal

Vincenzo Silani
Department of Neurology-Stroke Unit and Laboratory of Neuroscience
Department of Pathophysiology and Transplantation
Center for Neurotechnology and Brain Therapeutics
Università degli Studi di Milano
Milan, Italy

Adriano Chiò
Ferdinando Rossi School of Advanced Studies of Turin
ALS Regional Expert Center of Turin
Rita Levi Montalcini Department of Neuroscience, ALS Center
Torino, Italy

Andrea Calvo
Azienda Ospedaliera Città della Salute e della Scienza,
Rita Levi Montalcini Department of Neuroscience, ALS Centre
University of Torino
Turin, Italy

Francois Salachas
Paris ALS centre, Department of Neurology
Hôpital de la Pitié-Salpêtrière
Paris, France

William Camu
ALS Center, CHU Gui de Chauliac,
University of Montpellier
Montpellier, France

Susanne Petri
Department of Neurology,
Hannover Medical School
Hannover, Germany

Julian Grosskreutz
Hans-Berger Department of Neurology
Jena University Hospital
Jena, Germany

Magdalena Kuzma-Kozakiewicz
Department of Neurology
Neurodegenerative Disease Research Group
Medical University of Warsaw
Warsaw, Poland

Philip van Damme
KU Leuven – University of Leuven, Department of Neurosciences, Experimental Neurology and VIB Center for Brain & Disease Research and University Hospitals Leuven,
Department of Neurology
Leuven, Belgium

Orla Hardiman
Academic Unit of Neurology, Trinity Biomedical Sciences Institute,
Trinity College Dublin
Dublin, Republic of Ireland

Markus Weber
Neuromuscular Diseases Center/ALS Clinic,
Kantonsspital St. Gallen
St.Gallen, Switzerland

Pamela Shaw
Sheffield Institute for Translational Neuroscience and Sheffield NIHR Biomedical Research Centre for Translational Neuroscience and Neuroscience Research Institute,
Sheffield, UK

Ammar Al-Chalabi
Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, King’s College London*
London, UK

Mamede de Carvalho
Translational and Clinical Physiology Unit, Instituto de Medicina Molecular Faculty of Medicine, University of Lisbon
Neuroscience Department, Hospital de Santa Maria,
Centro Hospitalar Lisboa Norte
Lisboa, Portugal

References

1. Piao YS, Wakabayashi K, Kakita A, Yamada M, Hayashi S, Morita T, et al. Neuropathology with clinical correlations of sporadic amyotrophic lateral sclerosis: 102 autopsy cases examined between 1962 and 2000. Brain Pathol 2003;13:10–22.

2. Kurian KM, Forbes RB, Colville S, Swingler RJ. Cause of death and clinical grading criteria in a cohort of amyotrophic lateral sclerosis cases undergoing autopsy from the Scottish Motor Neurone Disease Register. J Neurol Neurosurg Psychiatry 2009;80:84–7.

3. Corcia P, Pradat PF, Salachas F, Bruneteau G, Forestier N, Seilhean D, et al. Causes of death in a post-mortem series of ALS patients. Amyotroph Lateral Scler 2008;9:59–62.

4. Burkhardt C, Neuwirth C, Sommacal A, Andersen PM, Weber M. Is survival improved by the use of NIV and PEG in amyotrophic lateral sclerosis (ALS)? A post-mortem study of 80 ALS patients. PLoS One. 2017 May 23;12(5):e0177555. 

5. https://www.ecdc.europa.eu/en/current-risk-assessment-novel-coronavirus-situation

6. https://www.dgm.org/aktuelles/aktuelles-meldungen/meldungen/coronavirus-hinweise-covid-19-virus-patientinnen-patienten

7. https://aisla.it/covid-19-e-sla-lesperto-risponde/

8. https://www.gov.pl/web/koronawirus; https://gis.gov.pl/aktualnosci/

9. https://covid19.min-saude.pt

10. https://www.mndassociation.org/mnd-and-coronavirus/;

11. https://www.gov.uk/government/publications/covid-19-guidance-on-social-distancing-and-for-vulnerable-people

12. https://t.co/DsgD2EZnXr

13. http://medicine.tcd.ie/neurology/

14. http://sitran.org/people/shaw/

15. https://www.bag.admin.ch/bag/de/home/krankheiten/ausbrueche-epidemien-pandemien/aktuelle-ausbrueche-epidemien/novel-cov/information-fuer-die-aerzteschaft/schutzmassnahmen.html#72080722

16. https://www.palliative.ch/de/fachbereich/task-forces/fokus-corona/

17. https://www.dgm.org/aktuelles/aktuelles-meldungen/meldungen/coronavirus-hinweise-covid-19-virus-patientinnen-patienten

18. WHO. Rational use of personal protective equipment for coronavirus disease 2019 (COVID-19). Interim guidance. 2020; https://apps.who.int/iris/bitstream/handle/10665/331215/WHO-2019-nCov-IPCPPE_use-2020.1-eng.pdf

19. Feng S, Shen C, Xia N, Song W, Fan M, Cowling BJ. Rational use of face masks in the COVID-19 pandemic. The Lancet Respiratory Medicine. 2020. DOI:https://doi.org/10.1016/S2213-2600(20)30134-X

20. Collins AS. Preventing Health Care–Associated Infections – Patient Safety Chapter 41 in Patient Safety and Quality: An Evidence-Based Handbook for Nurses. Hughes RG, editor. Agency for Healthcare Research and Quality (US). 2008.

21. WHO. Advice on the use of masks in the context of COVID-19. 2020. WHO/2019-nCov/IPC_Masks/2020.3

22. van Doremalen N, Bushmaker T, Morris DH, Holbrook MG, Gamble A, Williamson BN, et al. Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1. New England Journal of Medicine, 2020.

Amyotrophic Lateral Sclerosis and COVID-19 – Recommendations to patients and caregivers was last modified: April 15th, 2020 by Editor
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