Paper of the Month

For October 2021, we have selected: Spelman T. el al Treatment Escalation vs Immediate Initiation of Highly Effective Treatment for Patients With Relapsing-Remitting Multiple Sclerosis: Data From 2 Different National Strategies.

For October 2021, we have selected: Lopez Bernal J. et al, Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant: test-negative case–control study.

For September 2021, we have selected: Ramsden CE et al. Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial

For September 2021, we have selected: ''Aschman A et al. Association Between SARS-CoV-2 Infection and Immune-Mediated Myopathy in Patients Who Have Died'' and ''Suh J et al. Skeletal Muscle and Peripheral Nerve Histopathology in COVID-19''

Our research paper of the month is a pooled retrospective non-randomised cohort study, evaluating the functional and safety outcomes of direct to angiography (DTA) treatment paradigm vs repeated imagingin the different treatment windows and on-call hours vs regular hours in patients undergoing thrombectomy.

For August 2021, we have selected two COVID-19 papers of the month, investigating the effectiveness of the Covid-19 vaccines in England and Israel, respectively.

For July 2021, we have selected: Langezaal LCM et al. Endovascular Therapy for Stroke Due to Basilar-Artery Occlusion. N Engl J Med 2021; 384:1910-1920. DOI: 10.1056/NEJMoa2030297

For July 2021, we have selected: Greinacher A. et al, Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination. N Engl J Med. 2021 Jun 3;384(22):2092-2101. doi: 10.1056/NEJMoa2104840.

For May 2021, we have selected: Walgaard et al. Second intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis (SID-GBS): a double-blind, randomised, placebo-controlled trial. Lancet Neurol 2021; 20=:275-283. doi: 10.1016/S1474-4422(20)30494-4.

For June 2021, we have selected the following paper: Dagan N. et al. BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Mass Vaccination Setting. N Engl J Med 2021; 384:1412-1423. doi: 10.1056/NEJMoa2101765.

For May 2021, we have selected: Rentsch CT et al. Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study. BMJ 202;372:n311. doi: 10.1136/bmj.n311.

For May 2021, we have selected: Walgaard et al. Second intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis (SID-GBS): a double-blind, randomised, placebo-controlled trial. Lancet Neurol 2021; 20=:275-283. doi: 10.1016/S1474-4422(20)30494-4.

Paper of the month: Association Between Dispatch of Mobile Stroke Units and Functional Outcomes Among Patients With Acute Ischemic Stroke in Berlin

For April 2021, we have selected: Pun B.T. et al. Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study. Lancet Respir Med. 2021; 9:239-250. doi: 10.1016/S2213-2600(20)30552-X.

For March 2021, we have selected: Krienke C. et al., A non-inflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis. Science 2021; 371: 145-153. doi: 10.1126/science.aay3638.