COVID-19 AND NEUROLOGY In this useful consensus paper, the current clinical guidelines and research progress on the management of COVID-19 are summarized, emphasizing on its neurological manifestations.  The aim of consensus was to help neurologists to understand the occurrence, development… Continue Reading

COVID-19 AND NEUROLOGY During the COVID-19 outbreak, frontline healthcare workers were mandated to wear personal protective equipment (PPE) while caring for suspected or confirmed COVID-19 patients, which involved the donning of face masks, protective eyewear, gowns, surgical gloves and the… Continue Reading

COVID-19 AND NEUROLOGY Because most patients with MG are on immunosuppressive or immunomodulatory therapies and may also have respiratory muscle weakness, there is a theoretical concern that MG/LEMS patients may be at higher risk of contracting the infection or experiencing… Continue Reading

COVID-19 AND NEUROLOGY The aim of this multicenter study was to investigate and characterize the occurrence of olfactory and gustatory disorders in patients with laboratory-confirmed COVID-19 infection. A total of 417 mild-to-moderate COVID-19 patients were included in the study; in… Continue Reading

COVID-19 TREATMENT In this report, the authors describe outcomes in a cohort of patients hospitalized for severe Covid-19 who were treated with remdesivir on a compassionate-use basis. Remdesivir is a prodrug of a nucleotide analogue that is intracellularly metabolized to… Continue Reading

COVID-19 TREATMENT In this nice narrative review just published in JAMA, the authors summarize current evidence regarding major proposed treatments, repurposed or experimental, for COVID-19 and provides a summary of current clinical experience and treatment guidance for this novel epidemic… Continue Reading

Helbok R, Öztürk S On behalf of the Members of the EAN Scientific Panel Neurocritical care Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe disease are commonly admitted… Continue Reading

My name is Rita and I am a 4th year Neurology resident in a peripheral hospital of northern Portugal, which is located near one of the first COVID-19 pandemic outbreaks in Portugal, the city of Ovar. Although the first case… Continue Reading

In this correspondence, Zhao et al. report the first case of COVID-19 initially presenting with acute Guillain-Barré syndrome (GBS) suggesting a possible association between GBS and SARS-CoV-2 infection. The authors assumed that GBS associated with SARS-CoV-2 might follow the pattern… Continue Reading

In a case series of 214 patients with coronavirus disease 2019 (COVID-19) Mao et al., report that neurologic symptoms were seen in 36.4% of patients and were more common in patients with severe infection (45.5%) according to their respiratory status.… Continue Reading

In this brief report, Poyiadji et al. describe the first presumptive case of COVID-19–associated acute necrotizing encephalopathy (ANE) in a 50-year-old female patient who presented with a 3-day history of cough, fever, and altered mental status. Brain MRI demonstrated haemorrhagic… Continue Reading

This paper addresses the possible proposed neurotropic mechanisms of COVID-19 virus and its analogies and differences with SARS-CoV virus. Indeed, similar to SARS-CoV, COVID-19 virus exploits the angiotensin-converting enzyme 2 (ACE2) receptor to gain entry inside the cells. In particular,… Continue Reading

In this short report, Moriguchi et al., describe the first case of Meningitis/Encephalitis associated with SARS-CoV-2 who was brought in by ambulance. It is very interesting to note that the SARS-CoV-2 RNA was not detected in the nasopharyngeal swab but… Continue Reading

April 10, 2020 The number of subjects infected with SARS-Cov-2 is dramatically increasing worldwide since the beginning of this year. However, as reported in literature so far, only a few SARS-Cov-2–positive children have been admitted to paediatric departments and, generally… Continue Reading

Our country was relatively proactive in the containment measures it took, which meant that there was not a drastic and calamitous increase in the number of people infected and, necessarily, in the number of deaths caused by the virus.