In this longitudinal study, recently published in the European Journal of Neurology, the authors sought to describe the neurological manifestations of patients with COVID‐19 and gain pathophysiological insights especially with respect to the cytokine release syndrome (CRS).
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Covid‐19‐related encephalopathy: a case series with brain FDG‐PET/CT findings
September 1, 2020In this paper, recently published in the European Journal of Neurology, the authors reported four cases of COVID‐19‐related encephalopathy. The diagnosis was made in patients with confirmed COVID‐19 who presented with new‐onset cognitive disturbances, central focal neurological signs or seizures. -
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Self-diagnosed COVID-19 in people with multiple sclerosis: a community-based cohort of the UK MS Register
September 1, 2020In this paper, recently published in the Journal of Neurology, Neurosurgery and Psychiatry, the authors report initial findings of an ongoing community based COVID-19 study in a large UK-wide population of people with multiple sclerosis (pwMS) which coincided with the peak of the COVID-19 outbreak in the UK -
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Immunosuppression for intracranial vasculitis associated with SARS-CoV-2: therapeutic implications for COVID-19 cerebrovascular pathology
September 1, 2020Acute cerebrovascular disease, particularly ischaemic stroke, has emerged as a serious complication of COVID-19. -
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Correlates of critical illness-related encephalopathy predominate postmortem COVID-19 neuropathology
September 1, 2020In this paper recently published in Acta Neuropathologica the authors report on neuropathological findings from autopsy for a study cohort of seven COVID-19 patients, all of whom were positive for SARS-CoV-2 by nasopharyngeal swab testing, and compare their observations with those made in a SARS-CoV-2 negative control autopsy cohort comprising individuals with non-septic and systemic inflammatory/septic clinical courses. -
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Cerebrovascular diseases in COVID-19 infection: The state of the art
September 1, 2020The clinical syndrome of COVID-19 infection is complex and implies multiorgan involvement. -
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Neurological manifestations in 404 COVID‑19 patients in Washington State
September 1, 2020In this paper, recently published in the Journal of Neurology, the authors report neurological manifestations in 404 consecutive patients with COVID-19 seen in outpatient clinics and hospitalised between February 20, 2020 and May 4, 2020 at Evergreen Hospital, Kirkland, Washington, USA. -
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Impact of COVID-19 pandemic on cognition in Parkinson’s disease
September 1, 2020In this paper, recently published in Movement Disorders, the authors explored, through a structured questionnaire, the potential effects of COVID-19 pandemic and lockdown on cognition in Parkinson’s Disease (PD) patients. In particular, they studied 28 PD patients with cognitive disturbance (10 PD with subjective cognitive complaints [SCI]; 10 PD with mild cognitive impairment [MCI] and 8 PD with dementia [PDD]). -
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Movement disorders as a new neurological clinical picture in severe SARS-CoV-2 infection
September 1, 2020In this paper, recently published in the European Journal of Neurology, the authors identified and performed in depth clinical characterisation of a new type of delayed onset movement disorder in five patients who were admitted to the AP-HP intensive care unit (ICU) units for severe SARS-CoV-2 infection. -
In this paper, recently published in Annals of Internal Medicine, the authors describe 3 patients without previous neurological or autoimmune disorders who were diagnosed with myasthenia gravis after the onset of coronavirus disease 2019 (COVID-19).
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The EAN established MoUs with the ERN dedicated to Neuromuscular diseases and Rare Neurological Diseases.
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The European Medicines Agency’s annual report 2019 is now available on the Agency’s website.
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Breaking newsResearch
COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing
September 1, 2020In this paper, recently published in Clinical Infectious Diseases, the authors report a laboratory confirmed SARS-CoV-2 re-infection in a patient which occurred 4.5 months after the first episode. -
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Anticoagulation, Mortality, Bleeding and Pathology Among Patients Hospitalized with COVID-19: A Single Health System Study
September 1, 2020In this study, the authors examined the association of in-hospital anticoagulation (AC) in COVID-19 patients with in-hospital outcomes and described thromboembolic findings on autopsies. -
Breaking newsResearch
Delirium and adverse outcomes in hospitalized patients with COVID‐19.
September 1, 2020In this longitudinal observational study. recently published in the Journal of the American Geriatrics Society, the authors investigate the occurrence of delirium in hospitalised patients with COVID‐19 and explore its association with adverse outcomes