As a partner of the EBRAINS 2.0 project, the European Academy of Neurology (EAN) is leading the publication of the open-access European Journal of Neurology (EJoN) Special Issue, Digital Health Research in Clinical Neurosciences.
The Special Issue aims to showcase cutting-edge research combining neuroscience, clinical practice, digital technologies, and multi-scale data integration, highlighting how these advances can improve our understanding of the brain and support better patient care. The initiative is led by Guest Editors: Prof Thomas Berger, Prof Philippe Ryvlin, and Prof Maurizio Corbetta.
The Special Issue brings together a diverse range of contributions demonstrating the growing impact of digital health across neurological research and care. Topics include artificial intelligence in neuroimaging, neuropathology, stroke, epilepsy, Parkinson’s disease, and brain tumours, alongside emerging areas such as digital biomarkers, digital twins, machine learning, explainable AI, and large language models in neurology.
Several articles also focus on strengthening the foundations of digital neuroscience through collaborative research infrastructures, data-sharing platforms, federated registries, and harmonised approaches to imaging and clinical data collection. Together, these contributions illustrate how digital innovation is transforming the way neurological diseases are studied, diagnosed, and managed.
As EJoN is an open-access journal, articles from the Special Issue are already being published online as they are accepted and finalized. Additional manuscripts remain under review, and the collection will continue to expand over the coming months. EAN will provide a further update once the Special Issue has been formally completed.
Read the Special Issue articles published to date here: https://onlinelibrary.wiley.com/doi/toc/10.1111/(ISSN)1468-1331.digital-health-research
As part of its contribution to EBRAINS 2.0, EAN provided support for article processing charges for selected commissioned papers as an in-kind contribution. Alongside these commissioned articles, the Special Issue includes manuscripts submitted through the open call. All submissions were peer-reviewed and evaluated on scientific merit by the editorial team of EJoN.



