Literature Review (Grey)
Patients with COVID-19 are increasingly reported to suffer from a wide range of neurological complications, affecting both the central and peripheral nervous system. Among central manifestations, cognitive and behavioral symptoms are to date not exhaustively detailed. Furthermore, it is not clear whether these represent a combination of non-specific complications of a severe systemic disease, not differing from those usually seen in patients suffering from heterogenous pathological conditions affecting the central nervous system, or instead, they are a peculiar expression of COVID-19 neurotropism; in other words, if the infection has a coincidental or causal role in such patients. In this review the author examined both hypotheses, reporting opposite points of view, with the aim to stimulate discussion and raise awareness of the topic.
Stracciari A, Bottini G, Guarino M, Magni E, Pantoni L; “Cognitive and Behavioral Neurology” Study Group of the Italian Neurological Society. Cognitive and behavioral manifestations in SARS-CoV-2 infection: not specific or distinctive features? Neurol Sci. 2021 Apr 12:1–9. doi: 10.1007/s10072-021-05231-0