Research

The aim of this study, recently published in the Journal of Neurology, Neurosurgery and Psychiatry was, by a systematic review of the reported cases of GBS in SARS-CoV-2 infection, to clarify the clinical and electrophysiological phenotype, to discuss, on the basis of the available data, whether the disease mechanism could be parainfective or postinfective and to speculate on the possible pathogenesis.

In this multicentre retrospective observational cohort study recently published in Lancet Rheumatology, the authors investigate the association between tocilizumab exposure and hospital-related mortality among patients requiring intensive care unit (ICU) support for COVID-19.

Rapid and accurate diagnostic tests are essential for controlling the ongoing Covid-19 pandemic.

In this report from Budapest, Hungary, the authors compared several clinical features (including time parameters, rate of intravenous thrombolysis and endovascular therapies) of patients admitted to a university stroke-unit within a 2-month COVID-pandemic period (March and April of 2020) with an identical pre-COVID period of 2019.

For September 2020, we have selected: The RECOVERY Collaborative Group. Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report.

For September 2020, we have selected two complementary papers.

Evaluating blood pressure and heart rate changes upon standing helps screening for nOH at bedside.

A paper has just been published – Collaboration between palliative care and neurology: a survey of clinicians in Europe.

Guidelines for the Acute Treatment of Cerebral Edema in Neurocritical Care Patients

New-onset seizures in the context of SARS-CoV-2 infection

Epilepsy care during the COVID-19 pandemic

Disability through COVID-19 pandemic: Neurorehabilitation cannot wait

Here are the news from the Coma and Disorders of Consciousness panel for May and June, including feedback from the Virtual EAN Congress, new diagnostic and prognostic tools, personalized pain assessment methods and epidemiological data on dysphagia.

For August 2020, we have selected Turner R.S. et al. “Nilotinib Effects on Safety, Tolerability,and Biomarkers in Alzheimer’s Disease” Annals of Neurology 2020;88:183–194. doi: 10.1002/ana.25775. Epub 2020 May 28.

For August 2020, we have selected Rogers J.P. et al. “Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic” Lancet Psychiatry 2020; 7:611-627.