Paper of the Month

This study presents the findings of a systematic review and a collaborative individual patient data meta-analysis of clinical trials involving patients with acute ischaemic stroke and atrial fibrillation, who were treated with either early or delayed initiation of DOACs at approved dosages.

Our papers of the month for June are two studies that suggest that transplantation of dopaminergic progenitor cells into the striatum may confer meaningful clinical benefits for patients with Parkinson’s disease.

Our papers of the month for May are two papers present findings from recent trials evaluating the efficacy and safety of tolebrutinib in patients with multiple sclerosis.

Our Paper of the Month is a prospective cohort study conducted in the US, including participants from the Nurses’ Health Study (NHS) and the Health Professionals Follow-Up Study (HPFS).

EAN Website Editor, Letizia Leocani, talks to Raphael Wurm, lead author of the eanNews Paper of the Month for January 2025, 'Mood Alterations in the Prodromal Phase of Sporadic Creutzfeldt-Jakob Disease'

Our paper of the month for March is a phase 3 multicentre, double-blind, randomised trial investigating whether treatment with exenatide can slow the progression of Parkinson’s disease.

For February we have selected two co-papers of the month, each of which examines the safety and efficacy of a specific drug in the treatment of patients with generalised myasthenia gravis.

Our paper of the month compares drug prescription prior to the clinical onset of sporadic Creutzfeldt-Jakob disease in patients versus matched controls aiming to uncover potential risk or protective factors.

Our paper of the month highlights the findings of the stage 2 interim analysis from the first cycle of MND SMART, a phase 3, multi-arm, randomised, adaptive platform trial conducted across 20 centres in the UK.

Our paper of the month for November presents the findings from two large trials comparing the safety and efficacy of evobrutinib with teriflunomide in adults with a diagnosis of relapsing MS.

Our Paper of the Month for October is a phase 2, double-blind, randomised, placebo-controlled trial investigating the efficacy of a monoclonal antibody (Lu AG09222) that inhibits PACAP signalling.

Each month the eanNews editorial team reviews the scientific press for recently published papers of outstanding interest to neurologists. Here we present our selection for October 2024.

Our paper of the month for September updates the 2020 Lancet Commission report on the identification of risk factors for dementia, adding two more risk factors to the list.

Our paper of the month for August is a randomised controlled trial evaluating tenecteplase administered 4.5 to 24 hours after stroke onset in 516 Chinese patients.

Our paper of the month is an observational cohort study exploring the link between sleep measures and AD pathology in 319 participants (mean ± SD age: 61.5 ± 5.4 years; 47% female) from the Rotterdam Study, a prospective population-based study conducted in the Netherlands.