eanpages
  • General interest
    • All Executive Page Paper of the Month EAN News EAN Congress news COVID-19 Interviews
      EAN News

      EAN endorsed meeting in September 2022

      August 12, 2022

      Executive Page

      Executive Page: New President-Elect outlines aims for EAN’s future agenda

      August 1, 2022

      Paper of the Month

      Research Paper of the Month: Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke

      August 1, 2022

      EAN News

      Contribute to the EAN Neuro-Covid Registry (ENERGY) and be part of our growing global project

      July 29, 2022

      Executive Page

      Executive Page: New President-Elect outlines aims for EAN’s future agenda

      August 1, 2022

      Executive Page

      New EAN President, Prof. Paul Boon, identifies brain health, research agenda, and residents as key priorities

      July 8, 2022

      Executive Page

      Executive Page: packed programme for our happy reunion at EAN 2022 in Vienna

      June 3, 2022

      Executive Page Dear EAN members, dear friends, It is my pleasure to give you an update on behalf of the EAN Scientific Committee following a busy year since my appointment as chair. It has been a privilege to be so deeply involved in the scientific activities of the EAN and to work closely with an amazing community of people who are so dedicated to the advancement of neurology. One of the strongest threads within that community is the EAN’s group of Scientific Panels, which are often referred to as the organisation’s ‘scientific backbone’. The panels have a hand in everything the EAN does from a scientific point of view, including coordinating clinical research, disseminating good practice, assisting in planning the EAN annual congress, supporting the EAN’s educational efforts, and producing guidelines that assist neurologists in daily practice. All of this work requires a considerable amount of oversight, and this is why each panel is run by its own Management Group, elected by the panel members. Being a part of one of these Management Groups (PDF) is an opportunity to play a direct part in determining the direction of scientific progress within Europe, and I am excited to say that the call for applications to stand for election will be announced in September. All panel members and EAN individual members are eligible to apply to be candidates, with the vote being held among the existing panel members in autumn. I would like to urge every neurologist with a passion for the scientific future of their special area of interest to consider standing for election to the relevant Management Group and to look out for the call for applications later this month. I can tell you from personal experience that fulfilling a role such as this within the structure of the EAN is a fascinating and extremely rewarding experience. The chance to take on such a unique leadership position should not be missed! The most satisfying aspect of being involved in the EAN’s organisational structure is surely seeing all the hard work and planning come to fruition when a small idea evolves into a newly launched project. One such example is the 1st EAN Science School, taking place in Salzburg next March. The idea of the Science School is to offer early career neurologists with an interest in translational research a new avenue for learning about basic pathomechanisms of neurological disorders. Application for this very first edition, on ‘Pathophysiology of disorders of the nervous system’, closed last week and we have been delighted with the level of interest. It was a pleasure to be part of the task force in charge of planning this new project and I look forward to seeing it officially transferred to the hands of the Scientific Committee after a successful event and evaluation in spring. Of our ongoing activities, one of the most significant is the EAN Neuro-covid Registry, which aims to collate epidemiological data on neurological manifestations in patients with COVID-19 infection reported by neurologists in outpatient services, emergency rooms, and hospital departments. We currently have 1,542 patients entered in the database, from 35 centres across 23 countries. So far, 29 patients have been followed for 12 months and 387 have completed the 6-months follow up. This is a decent start, but I would like to strongly encourage EAN members and their institutions to get involved and contribute cases to what will become an invaluable resource for neurologists and clinicians to improve care for Covid-19 patients. Finally, I would like share a word on a forthcoming collaboration between EAN and the Human Brain Project in December, that I think will interest a lot of EAN members. The EAN-EBRAINS joint workshop on ‘The future of medical data sharing in clinical neurosciences’ will be a three-day virtual event that aims to discuss issues and challenges associated with data sharing in Europe, from ethics to data safety and privacy, including those specific to data federation, such as the development and validation of federated algorithms. The whole workshop is completely free of charge and registration is open until 25 November, so please check out the details and sign up! I wish you all a healthy and pleasant autumn and I look forward to updating you again. Best wishes Thomas Berger Chair of the EAN Scientific Committee

      Executive Page: Join the EAN Panels and reinforce our scientific backbone! (Plus ENERGY update, and our first Science School)

      May 1, 2022

      Paper of the Month

      Research Paper of the Month: Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke

      August 1, 2022

      Paper of the Month

      Research Paper of the Month: Association of intraventricular fibrinolysis with clinical outcomes in ICH: an individual participant data meta-analysis

      July 8, 2022

      Paper of the Month

      Covid-19 Paper of the month: Widespread white matter oedema in subacute COVID-19 patients with neurological symptoms

      July 8, 2022

      Paper of the Month

      Research Paper of the Month: Healthy lifestyle and life expectancy with and without Alzheimer’s dementia: population based cohort study

      June 3, 2022

      EAN News

      EAN endorsed meeting in September 2022

      August 12, 2022

      EAN News

      Executive Page: New President-Elect outlines aims for EAN’s future agenda

      August 1, 2022

      EAN News

      Research Paper of the Month: Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke

      August 1, 2022

      EAN News

      Contribute to the EAN Neuro-Covid Registry (ENERGY) and be part of our growing global project

      July 29, 2022

      EAN Congress news

      Video Interview: Sleep-Wake Panel Co-Chair, Dr. Evelina Pajediene

      July 28, 2022

      EAN Congress news

      Watch the full EAN 2022 Opening Session on our Vimeo channel!

      July 11, 2022

      EAN Congress news

      New EAN President, Prof. Paul Boon, identifies brain health, research agenda, and residents as key priorities

      July 8, 2022

      EAN Congress news

      Video Interview: WFN President, Prof. Wolfgang Grisold

      July 7, 2022

      COVID-19

      Contribute to the EAN Neuro-Covid Registry (ENERGY) and be part of our growing global project

      July 29, 2022

      COVID-19

      COVID-19 Breaking News: Case Series/Case Reports – July 2022

      July 18, 2022

      COVID-19

      COVID-19 Breaking News: Meta-analyses/systematic reviews – July 2022

      July 18, 2022

      COVID-19

      COVID-19 Breaking News: Cross-Sectional Case Control Studies – July 2022

      July 18, 2022

      Interviews

      Video Interview: Sleep-Wake Panel Co-Chair, Dr. Evelina Pajediene

      July 28, 2022

      Interviews

      Video: EAN supports World Brain Day

      July 19, 2022

      Interviews

      Video Interview: European Journal of Neurology Award winner, Dr. Jonathan Coutinho

      July 18, 2022

      Interviews

      Video Interview: WFN President, Prof. Wolfgang Grisold

      July 7, 2022

  • Academic/Scientific
    • All Breaking news Neurology updates Scientific committee reports Scientific panels reports Eur J Neurol Top 10 Articles Scientific Corner
      EAN News

      Contribute to the EAN Neuro-Covid Registry (ENERGY) and be part of our growing global project

      July 29, 2022

      Academic/Scientific

      2nd EAN Science School, 18-20 March 2023

      July 20, 2022

      Breaking news

      COVID-19 Breaking News: Case Series/Case Reports – July 2022

      July 18, 2022

      Breaking news

      COVID-19 Breaking News: Meta-analyses/systematic reviews – July 2022

      July 18, 2022

      Breaking news

      COVID-19 Breaking News: Case Series/Case Reports – July 2022

      July 18, 2022

      Breaking news

      COVID-19 Breaking News: Meta-analyses/systematic reviews – July 2022

      July 18, 2022

      Breaking news

      COVID-19 Breaking News: Cross-Sectional Case Control Studies – July 2022

      July 18, 2022

      Breaking news

      COVID-19 Breaking News: Observational studies – prospective longitudinal cohort – June 2022

      June 8, 2022

      Neurology updates

      Neurology Update: Palliative care

      July 6, 2021

      Neurology updates

      Neurology Update: Clinical Neurophysiology

      June 2, 2021

      Neurology updates Hannover Medical School

      Progressive multifocal leukoencephalopathy – promising therapeutic approach with allogeneic BK virus-specific T cells

      May 17, 2021

      Neurology updates

      Neurology Update: Neuroimmunology

      May 12, 2021

      Scientific committee reports

      Scientific Committee Snapshot: Didier Leys

      April 1, 2020

      Scientific committee reports

      Scientific Committee Snapshot: Rigmor Hojland

      February 26, 2020

      Scientific committee reports

      Scientific Committee Snapshot: Christian Enzinger

      December 1, 2019

      Scientific committee reports

      Scientific Committee Snapshot: Maurizio Leone

      November 1, 2019

      Scientific panels reports

      Coma and DOC Panel Update (May-June): news from the EAN Virtual Congress, personalized pain assessment, NIRS-EEG and machine learning to predict outcomes, prevalence of swallowing disorders and new multimodal predictive algorithms.

      August 11, 2020

      Scientific panels reports

      Statement of the EAN Sleep-Wake-Panel

      June 3, 2020

      Scientific panels reports

      Rare Neurological Diseases in the COVID-19 era: Suggestions for information to patients and caregivers

      May 13, 2020

      Scientific panels reports

      Scentific Panel of the Month: Higher Cortical Functions

      March 2, 2020

      Eur J Neurol

      Video Interview: European Journal of Neurology Award winner, Dr. Jonathan Coutinho

      July 18, 2022

      Eur J Neurol

      EAN NeuroCOVID-19 Task Force position paper on COVID-19 vaccination hesitancy among people with chronic neurological disorders

      May 2, 2022

      Eur J Neurol

      European Journal of Neurology welcomes new associate editors

      December 13, 2021

      Eur J Neurol

      New European guideline and expert statements on the management of narcolepsy in adults and children

      June 30, 2021

      Top 10 Articles

      EAN is proud to announce the 2020 Virtual Master Classes Christmas Special

      November 13, 2020

      Top 10 Articles

      EUROPEAN JOURNAL OF NEUROLOGY – TOP 15 ARTICLES 2018

      February 1, 2019

      Top 10 Articles

      Interview with Prof. Patrick Cras – UEMS Section of Neurology (SN)

      February 3, 2018

      Top 10 Articles

      Interview with Mr. Bertrand Daval and Mrs. Nathalie Paulus

      February 3, 2018

      Scientific Corner

      Join the EAN Guideline Workshop on 24 June!

      May 13, 2022

      Scientific Corner

      First EAN Science School proves a hit in Salzburg

      April 1, 2022

      Scientific Corner

      Invitation to the EAN-EBRAINS Joint Workshop on ‘The Future of Medical Data Sharing in Clinical Neurosciences’

      July 2, 2021

      Scientific Corner

      1st EAN Science School, 26-29 March 2022: “Pathophysiology of disorders of the nervous system”

      June 18, 2021

  • Educational
    • All eLearning Student Corner E-Brain Grand Rounds Resident and Research Fellows Fellowship reports Education corner
      Fellowship reports

      Clinical Fellowship Reports 2022 – Oxford, Bern, London

      July 28, 2022

      Academic/Scientific

      2nd EAN Science School, 18-20 March 2023

      July 20, 2022

      Fellowship reports

      Clinical Fellowship Reports 2021 – Bucharest & Padova

      July 15, 2022

      Fellowship reports

      Research Fellowship Report 2021 – Inselspital Bern, Switzerland

      July 15, 2022

      eLearning

      Listen now to ‘eanCast: Weekly Neurology’ our latest eLearning resource

      July 14, 2022

      eLearning

      EAN Campus: Your source for online neurology education!

      June 24, 2022

      eLearning

      eanCast: Weekly Neurology

      June 24, 2022

      eLearning

      Meet our new eLearning Associate Editors

      August 12, 2021

      Student Corner

      EAN 2022 ‘Why Neurology?’ essay contest winners

      June 2, 2022

      Student Corner

      Students’ Corner: A day in the life of a medical student in your country

      May 20, 2022

      Student Corner

      Student Teaser Fellowship winners 2022

      May 11, 2022

      Student Corner

      ‘Why Neurology?’ student essay competition: win a travel grant for a future EAN Congress!

      March 14, 2022

      E-Brain

      ebrain May update: new website and podcast series

      May 1, 2021

      E-Brain

      EBRA launches 3rd call for clusters

      May 1, 2020

      E-Brain

      News from ebrain

      February 28, 2020

      E-Brain

      ebrain to host the 2019 Neurology Formative Test Questions, from 15 April to 26 May

      April 1, 2019

      Grand Rounds

      eBrain: virtual case report from Belgium

      October 2, 2017

      Grand Rounds

      Free access to Ebrain for EAN members

      July 1, 2016

      Grand Rounds

      Ebrain granted Royal College of Physicians (UK) CPD/CME accreditation

      July 1, 2016

      Grand Rounds

      ebrain session of the month: neuromuscular junction

      February 1, 2016

      Resident and Research Fellows

      Workshop at EAN 2022 raises awareness of mentorship benefits

      July 5, 2022

      Resident and Research Fellows

      First ever UK Regional Teaching Course held in Liverpool, in person

      July 4, 2022

      Resident and Research Fellows

      RRFS Special Session – Unveiling research in Neurology: differences between basic, clinical and translational

      June 25, 2022

      Resident and Research Fellows

      23rd EAN Spring School – Report

      June 24, 2022

      Fellowship reports

      Clinical Fellowship Reports 2022 – Oxford, Bern, London

      July 28, 2022

      Fellowship reports

      Clinical Fellowship Reports 2021 – Bucharest & Padova

      July 15, 2022

      Fellowship reports

      Research Fellowship Report 2021 – Inselspital Bern, Switzerland

      July 15, 2022

      Fellowship reports

      Research Fellowship Report 2020 – Institut Necker Enfants Malades, Paris

      July 15, 2022

      Education corner

      Clinical Fellowship Reports 2022 – Oxford, Bern, London

      July 28, 2022

      Education corner

      Clinical Fellowship Reports 2021 – Bucharest & Padova

      July 15, 2022

      Education corner

      Research Fellowship Report 2021 – Inselspital Bern, Switzerland

      July 15, 2022

      Education corner

      Research Fellowship Report 2020 – Institut Necker Enfants Malades, Paris

      July 15, 2022

  • Other News
    • All EAN Staff Grant opportunities News from EAN member societies EBC EFNA News in general Patients societies reports Surveys Forum
      Other News

      The role of EAN in the European Medicine Agency

      August 2, 2022

      News from EAN member societies

      14 June: Special publication celebrates 10 years of the European Working Group of People with Dementia

      August 2, 2022

      News from EAN member societies

      14 June: Alzheimer Europe hosts European Parliament Lunch Debate examining EU and WHO policies on neurological conditions

      August 2, 2022

      News from EAN member societies

      22 June: Alzheimer Europe invites applications for its new Anti-Stigma Award

      August 2, 2022

      EAN Staff

      EAN Head Office Profiles: Patrycja & Martin

      July 28, 2022

      EAN Staff

      EAN Head Office Profiles: Anja S

      July 12, 2022

      EAN Staff

      EAN Head Office Profiles: Magda & Lindley

      June 7, 2022

      EAN Staff

      EAN Head Office Profiles: Julia & Maria

      April 4, 2022

      Grant opportunities

      1st EAN Science School, 26-29 March 2022: “Pathophysiology of disorders of the nervous system”

      June 18, 2021

      Grant opportunities

      European Commission: Innovation and novelty in medical devices and in vitro diagnostic devices; towards common concepts of innovation-related risk assessments

      November 1, 2019

      Grant opportunities

      GBS|CIDP Foundation International 2020 Research Grant Opportunity

      October 29, 2019

      Grant opportunities

      The Clinical Fellowship application deadline is approaching

      October 1, 2019

      News from EAN member societies

      14 June: Special publication celebrates 10 years of the European Working Group of People with Dementia

      August 2, 2022

      News from EAN member societies

      14 June: Alzheimer Europe hosts European Parliament Lunch Debate examining EU and WHO policies on neurological conditions

      August 2, 2022

      News from EAN member societies

      22 June: Alzheimer Europe invites applications for its new Anti-Stigma Award

      August 2, 2022

      News from EAN member societies

      Alzheimer Europe publishes new reports on ‘sex, gender and sexuality in the context of dementia’, and ‘dementia-inclusive initiatives and communities’

      April 5, 2022

      EBC

      Value of Treatment project releases results and calls to action

      March 29, 2022

      EBC

      Best practices for patient safety: An EU-wide view on the use of medicines off-label

      December 31, 2021

      EBC

      Creating synergies and showcasing innovation: Brain Innovation Days 2021

      November 30, 2021

      EBC

      Best practices for patient safety: Register now!

      October 28, 2021

      EFNA

      OneNeurology European Summit underlines urgent need to prioritise neurology and drive change

      December 31, 2021

      EFNA

      EFNA launch eLearning Platform for neurology advocates

      February 1, 2021

      EFNA

      ‘Me and My Brain’ – Art Competition winners announced!

      February 1, 2021

      EFNA

      Survey on the impact of COVID-19 on neurology service delivery

      November 1, 2020

      News in general

      EAN lecture at the International Neuro-Urology Society annual congress 2022

      May 25, 2022

      News in general

      EPA-EAN Joint Symposium: ‘Etiology and Treatment of the Long Covid-19 Syndrome’ and other highlights at the 30th European Congress of Psychiatry

      May 25, 2022

      News in general

      Organise an EAN-Day or EAN Regional Teaching Course in your Country!

      May 17, 2022

      News in general

      Value of Treatment project releases results and calls to action

      March 29, 2022

      Patients societies reports

      News from Alzheimer Europe

      March 2, 2020

      Patients societies reports

      News from the WHO

      January 9, 2020

      Patients societies reports

      News from EFIC and the European Pain Forum

      January 3, 2020

      Patients societies reports

      News from EFIC and the European Pain Forum

      January 2, 2020

      Surveys

      Survey: management of covert brain infarction

      October 29, 2021

      Surveys

      Driving with an intracranial tumor

      July 13, 2020

      Surveys

      SURVEY: Driving with an intracranial tumor

      June 25, 2020

      Surveys

      EAN SURVEY: Neurological Symptoms in COVID-19 Patients

      April 10, 2020

      Forum

      Call for Applications: e-Learning Platform Editor-in-Chief

      August 4, 2020

      Forum

      Neurological News from Denmark VI – the land of the 2nd EAN congress 2016: Pain Research in Denmark from a neurological perspective

      April 1, 2016

      Forum

      Neurological News from Denmark V – the land of the 2nd EAN congress 2016: Clinical Dementia Research in Denmark

      March 1, 2016

      Forum

      Updated recommendations to minimise the risk of the rare brain infection PML with Tysabri – Comment to EMA recommendation

      March 1, 2016

  • EAN
  • Congress 2022
  • EAN pages
  • Eur J Neurol
  • Virtual Congress

eanpages

  • General interest
    • All Executive Page Paper of the Month EAN News EAN Congress news COVID-19 Interviews
      EAN News

      EAN endorsed meeting in September 2022

      August 12, 2022

      Executive Page

      Executive Page: New President-Elect outlines aims for EAN’s future agenda

      August 1, 2022

      Paper of the Month

      Research Paper of the Month: Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke

      August 1, 2022

      EAN News

      Contribute to the EAN Neuro-Covid Registry (ENERGY) and be part of our growing global project

      July 29, 2022

      Executive Page

      Executive Page: New President-Elect outlines aims for EAN’s future agenda

      August 1, 2022

      Executive Page

      New EAN President, Prof. Paul Boon, identifies brain health, research agenda, and residents as key priorities

      July 8, 2022

      Executive Page

      Executive Page: packed programme for our happy reunion at EAN 2022 in Vienna

      June 3, 2022

      Executive Page Dear EAN members, dear friends, It is my pleasure to give you an update on behalf of the EAN Scientific Committee following a busy year since my appointment as chair. It has been a privilege to be so deeply involved in the scientific activities of the EAN and to work closely with an amazing community of people who are so dedicated to the advancement of neurology. One of the strongest threads within that community is the EAN’s group of Scientific Panels, which are often referred to as the organisation’s ‘scientific backbone’. The panels have a hand in everything the EAN does from a scientific point of view, including coordinating clinical research, disseminating good practice, assisting in planning the EAN annual congress, supporting the EAN’s educational efforts, and producing guidelines that assist neurologists in daily practice. All of this work requires a considerable amount of oversight, and this is why each panel is run by its own Management Group, elected by the panel members. Being a part of one of these Management Groups (PDF) is an opportunity to play a direct part in determining the direction of scientific progress within Europe, and I am excited to say that the call for applications to stand for election will be announced in September. All panel members and EAN individual members are eligible to apply to be candidates, with the vote being held among the existing panel members in autumn. I would like to urge every neurologist with a passion for the scientific future of their special area of interest to consider standing for election to the relevant Management Group and to look out for the call for applications later this month. I can tell you from personal experience that fulfilling a role such as this within the structure of the EAN is a fascinating and extremely rewarding experience. The chance to take on such a unique leadership position should not be missed! The most satisfying aspect of being involved in the EAN’s organisational structure is surely seeing all the hard work and planning come to fruition when a small idea evolves into a newly launched project. One such example is the 1st EAN Science School, taking place in Salzburg next March. The idea of the Science School is to offer early career neurologists with an interest in translational research a new avenue for learning about basic pathomechanisms of neurological disorders. Application for this very first edition, on ‘Pathophysiology of disorders of the nervous system’, closed last week and we have been delighted with the level of interest. It was a pleasure to be part of the task force in charge of planning this new project and I look forward to seeing it officially transferred to the hands of the Scientific Committee after a successful event and evaluation in spring. Of our ongoing activities, one of the most significant is the EAN Neuro-covid Registry, which aims to collate epidemiological data on neurological manifestations in patients with COVID-19 infection reported by neurologists in outpatient services, emergency rooms, and hospital departments. We currently have 1,542 patients entered in the database, from 35 centres across 23 countries. So far, 29 patients have been followed for 12 months and 387 have completed the 6-months follow up. This is a decent start, but I would like to strongly encourage EAN members and their institutions to get involved and contribute cases to what will become an invaluable resource for neurologists and clinicians to improve care for Covid-19 patients. Finally, I would like share a word on a forthcoming collaboration between EAN and the Human Brain Project in December, that I think will interest a lot of EAN members. The EAN-EBRAINS joint workshop on ‘The future of medical data sharing in clinical neurosciences’ will be a three-day virtual event that aims to discuss issues and challenges associated with data sharing in Europe, from ethics to data safety and privacy, including those specific to data federation, such as the development and validation of federated algorithms. The whole workshop is completely free of charge and registration is open until 25 November, so please check out the details and sign up! I wish you all a healthy and pleasant autumn and I look forward to updating you again. Best wishes Thomas Berger Chair of the EAN Scientific Committee

      Executive Page: Join the EAN Panels and reinforce our scientific backbone! (Plus ENERGY update, and our first Science School)

      May 1, 2022

      Paper of the Month

      Research Paper of the Month: Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke

      August 1, 2022

      Paper of the Month

      Research Paper of the Month: Association of intraventricular fibrinolysis with clinical outcomes in ICH: an individual participant data meta-analysis

      July 8, 2022

      Paper of the Month

      Covid-19 Paper of the month: Widespread white matter oedema in subacute COVID-19 patients with neurological symptoms

      July 8, 2022

      Paper of the Month

      Research Paper of the Month: Healthy lifestyle and life expectancy with and without Alzheimer’s dementia: population based cohort study

      June 3, 2022

      EAN News

      EAN endorsed meeting in September 2022

      August 12, 2022

      EAN News

      Executive Page: New President-Elect outlines aims for EAN’s future agenda

      August 1, 2022

      EAN News

      Research Paper of the Month: Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke

      August 1, 2022

      EAN News

      Contribute to the EAN Neuro-Covid Registry (ENERGY) and be part of our growing global project

      July 29, 2022

      EAN Congress news

      Video Interview: Sleep-Wake Panel Co-Chair, Dr. Evelina Pajediene

      July 28, 2022

      EAN Congress news

      Watch the full EAN 2022 Opening Session on our Vimeo channel!

      July 11, 2022

      EAN Congress news

      New EAN President, Prof. Paul Boon, identifies brain health, research agenda, and residents as key priorities

      July 8, 2022

      EAN Congress news

      Video Interview: WFN President, Prof. Wolfgang Grisold

      July 7, 2022

      COVID-19

      Contribute to the EAN Neuro-Covid Registry (ENERGY) and be part of our growing global project

      July 29, 2022

      COVID-19

      COVID-19 Breaking News: Case Series/Case Reports – July 2022

      July 18, 2022

      COVID-19

      COVID-19 Breaking News: Meta-analyses/systematic reviews – July 2022

      July 18, 2022

      COVID-19

      COVID-19 Breaking News: Cross-Sectional Case Control Studies – July 2022

      July 18, 2022

      Interviews

      Video Interview: Sleep-Wake Panel Co-Chair, Dr. Evelina Pajediene

      July 28, 2022

      Interviews

      Video: EAN supports World Brain Day

      July 19, 2022

      Interviews

      Video Interview: European Journal of Neurology Award winner, Dr. Jonathan Coutinho

      July 18, 2022

      Interviews

      Video Interview: WFN President, Prof. Wolfgang Grisold

      July 7, 2022

  • Academic/Scientific
    • All Breaking news Neurology updates Scientific committee reports Scientific panels reports Eur J Neurol Top 10 Articles Scientific Corner
      EAN News

      Contribute to the EAN Neuro-Covid Registry (ENERGY) and be part of our growing global project

      July 29, 2022

      Academic/Scientific

      2nd EAN Science School, 18-20 March 2023

      July 20, 2022

      Breaking news

      COVID-19 Breaking News: Case Series/Case Reports – July 2022

      July 18, 2022

      Breaking news

      COVID-19 Breaking News: Meta-analyses/systematic reviews – July 2022

      July 18, 2022

      Breaking news

      COVID-19 Breaking News: Case Series/Case Reports – July 2022

      July 18, 2022

      Breaking news

      COVID-19 Breaking News: Meta-analyses/systematic reviews – July 2022

      July 18, 2022

      Breaking news

      COVID-19 Breaking News: Cross-Sectional Case Control Studies – July 2022

      July 18, 2022

      Breaking news

      COVID-19 Breaking News: Observational studies – prospective longitudinal cohort – June 2022

      June 8, 2022

      Neurology updates

      Neurology Update: Palliative care

      July 6, 2021

      Neurology updates

      Neurology Update: Clinical Neurophysiology

      June 2, 2021

      Neurology updates Hannover Medical School

      Progressive multifocal leukoencephalopathy – promising therapeutic approach with allogeneic BK virus-specific T cells

      May 17, 2021

      Neurology updates

      Neurology Update: Neuroimmunology

      May 12, 2021

      Scientific committee reports

      Scientific Committee Snapshot: Didier Leys

      April 1, 2020

      Scientific committee reports

      Scientific Committee Snapshot: Rigmor Hojland

      February 26, 2020

      Scientific committee reports

      Scientific Committee Snapshot: Christian Enzinger

      December 1, 2019

      Scientific committee reports

      Scientific Committee Snapshot: Maurizio Leone

      November 1, 2019

      Scientific panels reports

      Coma and DOC Panel Update (May-June): news from the EAN Virtual Congress, personalized pain assessment, NIRS-EEG and machine learning to predict outcomes, prevalence of swallowing disorders and new multimodal predictive algorithms.

      August 11, 2020

      Scientific panels reports

      Statement of the EAN Sleep-Wake-Panel

      June 3, 2020

      Scientific panels reports

      Rare Neurological Diseases in the COVID-19 era: Suggestions for information to patients and caregivers

      May 13, 2020

      Scientific panels reports

      Scentific Panel of the Month: Higher Cortical Functions

      March 2, 2020

      Eur J Neurol

      Video Interview: European Journal of Neurology Award winner, Dr. Jonathan Coutinho

      July 18, 2022

      Eur J Neurol

      EAN NeuroCOVID-19 Task Force position paper on COVID-19 vaccination hesitancy among people with chronic neurological disorders

      May 2, 2022

      Eur J Neurol

      European Journal of Neurology welcomes new associate editors

      December 13, 2021

      Eur J Neurol

      New European guideline and expert statements on the management of narcolepsy in adults and children

      June 30, 2021

      Top 10 Articles

      EAN is proud to announce the 2020 Virtual Master Classes Christmas Special

      November 13, 2020

      Top 10 Articles

      EUROPEAN JOURNAL OF NEUROLOGY – TOP 15 ARTICLES 2018

      February 1, 2019

      Top 10 Articles

      Interview with Prof. Patrick Cras – UEMS Section of Neurology (SN)

      February 3, 2018

      Top 10 Articles

      Interview with Mr. Bertrand Daval and Mrs. Nathalie Paulus

      February 3, 2018

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Symposium 6 – New evidences to tackle major health issues in stroke

July 4, 2022

by Benedetta Bodini

This very interesting symposium on New evidence to tackle major health issues in stroke was organised in cooperation with the European Stroke Organisation. It started with a lecture by Prof. Georgios Tsivgoulis who discussed the relevance of detecting atrial fibrillation to prevent stroke. He started by indicating that, among all the causes of ischaemic stroke, the cardioembolic cause represents a major component. However, he underlined that an indiscriminate anticoagulation of all embolic strokes of undetermined source (ESUS) is not supported by randomised controlled trials comparing the use of oral anticoagulants with aspirin in this type of patients. Moreover, indiscriminate anticoagulation in these patients results in very high costs due to an increased number of bleeding events in patients treated with oral anticoagulants. Indeed, we have to consider that ESUS is a heterogeneous group of cerebrovascular disorders with multiple etiologies of cerebral embolism. Implantable cardiac monitoring has been shown to be able to detect atrial fibrillation only in a minority of patients with ESUS, with a key predictor of eventually finding atrial fibrillation being the increased duration of monitoring. Interestingly, subclinical device-detected atrial fibrillation has been shown to have the potential to predict clinical atrial fibrillation and increased stroke risk. Tsivgoulis then examined the different methods to monitor cardiac rhythm in individuals with stroke risk factors and indicated that there is clear evidence suggesting that the diagnostic yield increases with duration, dispersion and number of screenings, although all strategies (including serial 30-days Holter monitoring) have low yield comparable with the implantable cardiac monitoring. In a recent study, Tsivouglis’s team found that paroxysmal atrial fibrillation detection was higher in the cohort with implantable cardiac monitoring compared with the group with traditional Holter monitoring. Patients with implantable cardiac monitoring were also found to have significantly higher rates of anticoagulation initiation and lower risk of stroke recurrence during follow-up. These results were confirmed in a large meta-analysis recently published in Neurology (Tsivgoulis et al, 2022). He then indicated that even atrial fibrillation detected after stroke (both the cardiogenic and the neurogenic variant) is associated with a significant increase in the risk of recurrent stroke and death. Overall, the international recommendations indicate that in stroke patients, additional cardiac rhythm monitoring by long-term non-invasive ECG monitors or implantable loop recorders should be employed to document silent atrial fibrillation. Moreover, in patients with cryptogenic stroke (particularly in elderly patients, with cardiovascular risk factors or comorbidities, indices of left atrial remodeling, high C2HEST score), implantation of a cardiac monitor is reasonable to optimise detection of silent atrial fibrillation.

In the second lecture of the session, Prof. Hugh Marcus discussed the treatment of vascular risk to prevent dementia. He started by indicating that dementia incidence is declining over time and there could be a relationship with a similar decline over time of cardiovascular diseases. Vascular risk factors may increase the risk of Alzheimer’s disease by the impact of vascular damage in reducing brain resources or through a direct effect on Alzheimer’s disease pathology. Epidemiological studies clearly suggest that cardiovascular risk factors, particularly in middle-aged people, significantly increase the risk of Alzheimer’s disease. Moreover, prospective studies and randomised controlled studies have shown that effectively treating hypertension reduces the risk of developing cognitive deficits and Alzheimer’s disease. Marcus then indicated that the evidence is less clear on the impact of controlling diabetes and cholesterol levels on the evolution of cognition over time. In the final part of his lecture, he discussed the important question of whether atrial fibrillation is associated with dementia. Indeed, atrial fibrillation may be involved in the pathogenesis of dementia through the induction of a thrombotic state, but also through different mechanisms, such as inflammation and hypoperfusion. A recent meta-analysis has clearly indicated that atrial fibrillation is a risk factor for cognitive impairment, and that effective control of atrial fibrillation results in a significant reduction of the risk of dementia.

The third lecture, which was focused on the treatment of asymptomatic carotid artery stenosis was presented by Prof. Allison Hallidays. She started with a reminder that worldwide more than one million strokes per year result from carotid disease. This includes carotid plaques with arteriogenic emboli and flow reducing carotid stenosis. In asymptomatic patients, multiple clinical trials have consistently shown that carotid endarterectomy significantly reduces the risk of any type of first stroke (both ipsilateral and contralateral) compared with medical treatment (blood pressure lowering, anti-thrombotic, and statin treatments). In 2019, a preplanned pooled analysis compared stenting with endarterectomy in a group of symptomatic patients, and found that the risk of stroke following the two procedures was almost identical. Several studies have compared these two procedures in asymptomatic patients. Multiple studies did not find any clear evidence supporting the superiority of stenting or surgery in preventing stroke. The recent ACST-2 trial confirmed a 1% 30-day risk in each group of procedural death or disabling stroke and a 2.5% five-year risk in each group of non-procedural disabling or fatal strokes. However, with stenting, there was a 1-2% excess risk of non-disabling strokes. Medical therapy for asymptomatic patients includes high blood pressure control (with an objective to lower blood pressure < 140/80 and maybe 120 systolic) and antithrombotic treatment with low-dose aspirin and dipyridamole or clopidogrel or possibly dipyridamole monotherapy (200 mg twice daily) if patients are intolerant or allergic to both aspirin and clopidogrel. As far as cholesterol level control is concerned, carotid guidelines suggest an LDL-cholesterol target of < 1.8 mmol/L, obtained with statins or PCSK9 inhibitors.

In the final lecture of the session, Prof. Jesse Dawson discussed the role of neuromodulation in post stroke recovery. There are several mechanisms that lead to functional impairment after stroke, including neuronal cell death, altered neuronal connectivity and secondary degeneration, and each of these mechanisms could be potentially addressed to improve functional recovery. Neuromodulation is defined as the alteration of nerve activity through targeting delivery of a stimulus, such as electrical stimulation or chemical agents, to specific neurological sites in the body. Methods of neurostimulation include repetitive stimulation, paired stimulation and closed loop stimulation. Most studies have looked at the use of neuromodulation to improve motor impairment, but several progresses have been made in using this approach to treat spasticity, dysphagia and to increase collateral blood flow. A recent study explored the effects of vagus nerve stimulation (VNS) on patients with stroke and found that the VNS group already had a significant clinical improvement one day after the stroke, which was maintained three months afterwards (Dawson et al, Lancet 2021). Following this study, the FDA has approved this approach to treat moderate to severe upper extremity motor deficits associated with chronic ischaemic strokes. As far as sphenopalatine ganglion stimulation is concerned, Dawson presented the results of a study (Bornstein et al, Lancet 2019) which demonstrated that this approach is safe for patients with acute ischaemic stroke and is likely to improve functional outcome. He concluded his lecture saying that neuromodulation techniques allow a degree of precision and timing which cannot be achieved by drugs and that these techniques have already begun to show success in pivotal trials.

Symposium 6 – New evidences to tackle major health issues in stroke was last modified: July 4th, 2022 by Simon Lee
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