In this correspondence, Zhao et al. report the first case of COVID-19 initially presenting with acute Guillain-Barré syndrome (GBS) suggesting a possible association between GBS and SARS-CoV-2 infection. The authors assumed that GBS associated with SARS-CoV-2 might follow the pattern of a parainfectious profile, instead of the classic postinfectious profile, as reported in GBS associated with Zika virus. However, more cases with epidemiological data are necessary to support a causal relationship between GBS and COVID-19 infection.
by Marialuisa Zedde and Francesco Cavallieri